BioGeM

{{Infobox Institute

| name = BioGeM Institute

| image = BioGeM logo.svg

| image_size = 150px

| mission = Biological research

| focus = Molecular genetics

| established = 2006

| president = Ortensio Zecchino

| faculty =

| staff =

| budget =

| endowment =

| debt =

| city = Ariano Irpino

| state = Italy

| coor = {{Coord|41.199442|N|15.134100|E|source:Wikidata|display=inline,title}}

| address = Camporeale

| website = http://www.biogem.it

| footnotes = {{Location map|Italy

|label = BioGeM (Ariano Irpino)

|position = right

|lat = 41.199442

|long = 15.134100

|border = none

|float = center

|width = 250

|caption = Location in Italy

}}

}}

The BioGeM Institute (Biologia e Genetica Molecolare, "Biology and Molecular Genetics") is a nonprofit consortium formed by the National Research Council (CNR), the University of Naples "Federico II", the LUMSA of Rome, the Trieste AREA Science Park, the University of Udine, the Stazione Zoologica Anton Dohrn of Naples, the University of Sannio in Benevento, the University of Foggia, the University of Milan Bicocca, the

Second University and the Suor Orsola Benincasa University of Naples, the Chamber of Commerce of Avellino and the local mountain community of Ufita Valley.{{cite web|url=http://www.biogem.it/index-eng.html|title=Home|website=Biogem}}

BioGeM was inaugurated in 2006 by Nobel laureate Rita Levi Montalcini{{cite web|url=http://ricerca.repubblica.it/repubblica/archivio/repubblica/2006/07/16/montalcini-battezza-biogem-premio-alla-ricerca-del.html|title=Montalcini battezza Biogem 'Premio alla ricerca del Sud'|trans-title=Rita Levi Montalcini christens Biogem: 'That's a prize for southern Italy's research'|website=La Repubblica|date=16 July 2006 |language=Italian}} and comprises research laboratories, services and teaching facilities. Scientific research, led by “Gaetano Salvatore” Genetics Research Institute (IRGS), takes place within Genetics and Translational Medicine (GTM) department and is aimed at understanding biological mechanisms and identifying the genes involved in the development and proliferation of various human diseases; the research is based on the use of animal models raised in a high level laboratory{{cite report|date=2014-09-10|url=http://www.fofi.it/doc_fofi/rassegna8400831.pdf|author=Fulvio Bufi|title=In Irpinia la biogenetica vince anche senza Rete|trans-title=In Irpinia biogenetics wins even without the web|publisher=Federazione ordine dei farmacisti|pages=16–26|language=it}} after the approval of the ethics committee for animal experimentation.{{cite journal|pmc=5399181|title=Cell Death and Disease|volume=6|issue=10|pages=e1959–|journal=Cell Death & Disease|year=2015|last1=Carchia|first1=E.|last2=Porreca|first2=I.|last3=Almeida|first3=P. J.|last4=d'Angelo|first4=F.|last5=Cuomo|first5=D.|last6=Ceccarelli|first6=M.|last7=De Felice|first7=M.|last8=Mallardo|first8=M.|last9=Ambrosino|first9=C.|pmid=26512966|doi=10.1038/cddis.2015.319}} Research primarily aims at fighting cancer and degenerative diseases,{{cite book|author=Lino Patruno|title=Il meglio Sud: attraversare il deserto, superare il divario|trans-title=The best South: crossing the desert to bridge the gap|language=Italian|url=https://books.google.com/books?id=U1tQCgAAQBAJ&q=capecchi+biogem+migliore+europa&pg=PT191|isbn=9788849845877|date=2015-08-06|publisher=Rubbettino Editore }}{{cite web|url=http://unilink.it/biogem-nuova-scoperta-nella-lotta-al-cancro/|title=Biogem: nuova scoperta nella lotta al cancro|trans-title=A new discovery for the fight against cancer|website=Link Campus University|language=Italian|access-date=2019-01-05|archive-date=2018-06-27|archive-url=https://web.archive.org/web/20180627190728/http://unilink.it/biogem-nuova-scoperta-nella-lotta-al-cancro/|url-status=dead}} often in collaboration with international groups.{{cite web|url=http://www.italoeuropeo.co.uk/2015/09/30/biogem-meeting-prof-zichichi-from-the-beauty-of-creation-to-the-superworld/|title=Biogem:meeting. Prof. Zichichi: from the beauty of creation to the superworld|website=L'italo-europeo|date=30 September 2015 }}{{cite journal|title=A metabolic function of FGFR3-TACC3 gene fusions in cancer|journal=Nature|year=2018|doi=10.1038/nature25171|last1=Frattini|first1=Véronique|last2=Pagnotta|first2=Stefano M.|last3=Tala|last4=Fan|first4=Jerry J.|last5=Russo|first5=Marco V.|last6=Lee|first6=Sang Bae|last7=Garofano|first7=Luciano|last8=Zhang|first8=Jing|last9=Shi|first9=Peiguo|last10=Lewis|first10=Genevieve|last11=Sanson|first11=Heloise|last12=Frederick|first12=Vanessa|last13=Castano|first13=Angelica M.|last14=Cerulo|first14=Luigi|last15=Rolland|first15=Delphine C. M.|last16=Mall|first16=Raghvendra|last17=Mokhtari|first17=Karima|last18=Elenitoba-Johnson|first18=Kojo S. J.|last19=Sanson|first19=Marc|last20=Huang|first20=Xi|last21=Ceccarelli|first21=Michele|last22=Lasorella|first22=Anna|last23=Iavarone|first23=Antonio|volume=553|issue=7687|pages=222–227|pmid=29323298|pmc=5771419|bibcode=2018Natur.553..222F}}{{cite journal|title=The molecular landscape of glioma in patients with Neurofibromatosis 1|journal=Nature Medicine|year=2019|doi=10.1038/s41591-018-0263-8|last1=d'Angelo|first1=Fulvio|last2=Ceccarelli|first2=Michele|last3=Tala|last4=Garofano|first4=Luciano|last5=Zhang|first5=Jing|last6=Frattini|first6=Véronique|last7=Caruso|first7=Francesca P.|last8=Lewis|first8=Genevieve|last9=Alfaro|first9=Kristin D.|last10=Bauchet|first10=Luc|last11=Berzero|first11=Giulia|last12=Cachia|first12=David|last13=Cangiano|first13=Mario|last14=Capelle|first14=Laurent|last15=De Groot|first15=John|last16=Dimeco|first16=Francesco|last17=Ducray|first17=François|last18=Farah|first18=Walid|last19=Finocchiaro|first19=Gaetano|last20=Goutagny|first20=Stéphane|last21=Kamiya-Matsuoka|first21=Carlos|last22=Lavarino|first22=Cinzia|last23=Loiseau|first23=Hugues|last24=Lorgis|first24=Véronique|last25=Marras|first25=Carlo E.|last26=McCutcheon|first26=Ian|last27=Nam|first27=Do-Hyun|last28=Ronchi|first28=Susanna|last29=Saletti|first29=Veronica|last30=Seizeur|first30=Romuald|volume=25|issue=1|pages=176–187|pmid=30531922|pmc=6857804|display-authors=1}}

Furthermore, the pharmacological research is carried out by a proper department named Medicinal Investigational Research (MIR), whose task covers the experimental verification of new drugs and the release of the related certifications.{{cite web|url=http://mobile.ilsole24ore.com/solemobile/main/art/impresa-e-territori/2013-09-24/biogem-eccellenza-ricerca-genetica-164643.shtml?uuid=Abn5M5aI|title=Biogem, da eccellenza nella ricerca genetica a certificatore dello sviluppo dei farmaci|trans-title=Biogem, an excellence in genetic research to be a certificator of drugs' development|website=Il Sole 24 ore Newspaper|language=Italian|access-date=2019-01-10|archive-url=https://web.archive.org/web/20180530091053/http://mobile.ilsole24ore.com/solemobile/main/art/impresa-e-territori/2013-09-24/biogem-eccellenza-ricerca-genetica-164643.shtml?uuid=Abn5M5aI|archive-date=2018-05-30|url-status=dead}} Furthermore, the training activities take place in a specific functional area named Life and Mind Science School (LIMSS).

Since 2010 Biogem has yearly hosted a meeting named Le due culture ("The two cultures") which over the years has been attended by a number of Nobel laureates{{cite web|url=http://mobile.ilsole24ore.com/solemobile/main/art/tecnologie/2016-08-30/i-nobel-tornano-biogem-festival-due-culture-173527.shtml?uuid=ADuFvMCB|title=I Nobel tornano a Biogem al Festival delle due culture|trans-title=The Nobel laureates come back to Biogem at the Two cultures festival|website=Il Sole 24 Ore Newspaper|language=Italian|access-date=2019-01-01|archive-url=https://web.archive.org/web/20180627185536/http://mobile.ilsole24ore.com/solemobile/main/art/tecnologie/2016-08-30/i-nobel-tornano-biogem-festival-due-culture-173527.shtml?uuid=ADuFvMCB|archive-date=2018-06-27|url-status=dead}} and also (in 2018) the president of Italy Sergio Mattarella.{{cite web|url=https://www.quirinale.it/elementi/17610|title=Il Presidente Mattarella alla giornata inaugurale della X edizione del meeting "Le due culture"|trans-title=The president of Italy Mattarella is staying at the first day of "Two cultures meeting" - 10th edition|website=The President of the Italian Republic|language=Italian}}{{cite web|url=https://video.repubblica.it/edizione/napoli/ricerca-mattarella-visita-la-biogem-e-stringe-la-mano-agli-studenti/313683/314312|title=Ricerca, Mattarella visita la Biogem e stringe la mano agli studenti|trans-title=Research: the president Mattarella visits Biogem and shakes hands with students|website=La Repubblica Newspaper|date=2018-09-05| language=Italian}} The objective of the meeting is to find a common ground between humanistic and scientific knowledge.{{cite web|url=http://napoli.repubblica.it/cronaca/2015/08/12/foto/ariano_irpino_il_meeting_le_due_culture_aprira_le_porte_di_biogem-120858560/1/|title=Ariano Irpino, il meeting Le Due Culture aprirà le porte di Biogem|trans-title=Ariano Irpino: The 'Two cultures meeting' opens Biogem's door|website=La Repubblica Newspaper|date=12 August 2015|language=Italian}}

The institute also hosts an office of Sopra Steria, a French company specialized in consulting and digital services.{{cite web|url=https://www.ilsole24ore.com/art/sopra-steria-si-rafforza-ad-ariano-irpino-AEYfgsBC|title=Sopra Steria si rafforza ad Ariano Irpino|trans-title=Sopra Steria strengthens in Ariano Irpino|author=Vera Viola|website=Il Sole 24 ore|date=22 October 2022|language=Italian|url-status=live|archive-url=https://web.archive.org/web/20221105151057/https://www.ilsole24ore.com/art/sopra-steria-si-rafforza-ad-ariano-irpino-AEYfgsBC|archive-date=5 November 2022}} Since 2013 Biogem has a forensic genetics laboratory too.{{cite web|url=http://www.ordinemedicinapoli.it/2053-inaugurazione-laboratorio-genetica-forense-biogem.php|title=Inaugurazione Laboratorio Genetica Forense Biogem|trans-title=Inauguration of the forensic genetics laboratory at Biogem|website=Ordine dei medici di Napoli|publisher=General medical council of Naples|language=Italian}}