Biochemical recurrence

Biochemical recurrence is a rise in the blood level of prostate-specific antigen (PSA) in prostate cancer patients after treatment with surgery or radiation. Biochemical recurrence may occur in patients who do not have symptoms. It may mean that the cancer has come back. Also called PSA failure and biochemical relapse.[http://www.cancer.gov/dictionary?CdrID=543628 Biochemical recurrence]

It is used to detect metastatic progression of the prostate cancer.[http://ascopubs.org/doi/pdf/10.1200/jco.2005.04.0756 Defining Biochemical Recurrence of Prostate Cancer After Radical Prostatectomy: A Proposal for a Standardized Definition. 2005]

References

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Further reading

  • [http://wiki.cancer.org.au/australia/Guidelines:Prostate_cancer/Management/Locally_advanced_and_metastatic/Biochemical_relapse Guidelines:Prostate cancer/Management/Locally advanced and metastatic/Biochemical relapse] alternative causes, and implications for treatment
  • [http://ascopubs.org/doi/pdf/10.1200/jco.2005.04.0756 Defining Biochemical Recurrence of Prostate Cancer After Radical Prostatectomy: A Proposal for a Standardized Definition] 10 definitions compared.