Bivatuzumab mertansine

{{Short description|Chemical compound}}

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| verifiedrevid = 447729255

| image = Mertansine mab structure.svg

| type = mab

| mab_type = mab

| source = zu/o

| target = CD44 v6

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Bivatuzumab mertansine is a combination of bivatuzumab, a humanized monoclonal antibody, and mertansine, a cytotoxic agent. It is designed for the treatment of squamous cell carcinoma.{{cite journal | vauthors = Tijink BM, Buter J, de Bree R, Giaccone G, Lang MS, Staab A, Leemans CR, van Dongen GA | display-authors = 6 | title = A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus | journal = Clinical Cancer Research | volume = 12 | issue = 20 Pt 1 | pages = 6064–72 | date = October 2006 | pmid = 17062682 | doi = 10.1158/1078-0432.CCR-06-0910 | doi-access = free }}

References

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{{Monoclonals for tumors}}

Category:Monoclonal antibodies for tumors

Category:Experimental cancer drugs

Category:Antibody-drug conjugates

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