Blautia wexlerae
{{Short description|Species of bacterium}}
{{speciesbox
| taxon = Blautia wexlerae
| authority = Liu et al. 2008
| synonyms =
}}
Blautia wexlerae is an anaerobic and gram-positive bacteria that lives in the human intestine.{{cite web |last1=Podstawka |first1=Adam |title=Blautia wexlerae Walcc: 14507 {{!}} Type strain {{!}} DSM 19850, ATCC BAA 1564, JCM 17041, KCTC 5965, WAL 14507 {{!}} BacDiveID:18075 |url=https://bacdive.dsmz.de/strain/18075 |website=bacdive.dsmz.de |access-date=23 May 2023 |language=en}}{{cite web |title=Summary of Blautia wexlerae DSM 19850, version 27.0 |url=https://biocyc.org/organism-summary?object=GCF_000484655 |website=biocyc.org |access-date=22 May 2023 |language=en}}
Studies of gut microbiota have found indications that higher levels of B. wexlerae may decrease obesity in mice and humans.{{cite journal |title=Gut microbiota signatures of vulnerability to food addiction in mice and humans |date=2024 |last1=Samulėnaitė |first1=Solveiga |last2=García-Blanco |first2=Alejandra |last3=Mayneris-Perxachs |first3=Jordi |last4=Domingo-Rodríguez |first4=Laura |last5=Cabana-Domínguez |first5=Judit |last6=Fernàndez-Castillo |first6=Noèlia |last7=Gago-García |first7=Edurne |last8=Pineda-Cirera |first8=Laura |last9=Burokas |first9=Aurelijus |last10=Espinosa-Carrasco |first10=Jose |last11=Arboleya |first11=Silvia |last12=Latorre |first12=Jessica |last13=Stanton |first13=Catherine |last14=Hosomi |first14=Koji |last15=Kunisawa |first15=Jun |last16=Cormand |first16=Bru |last17=Fernández-Real |first17=Jose Manuel |last18=Maldonado |first18=Rafael |last19=Martín-García |first19=Elena |journal=Gut |doi=10.1136/gutjnl-2023-331445 |pmid=38926079 |doi-access=free |pmc=11503113 }} B. wexlerae produces acetylcholine and carbohydrate metabolites (ex. succinate, lactate, acetate). These may modify the gut environment, including the bacterial and SCFA composition of the gut microbiota. Thus, B. wexlerae may offer various, numerous, and diverse benefits for health maintenance.{{cite journal |last1=Hosomi |first1=Koji |last2=Saito |first2=Mayu |last3=Park |first3=Jonguk |last4=Murakami |first4=Haruka |last5=Shibata |first5=Naoko |last6=Ando |first6=Masahiro |last7=Nagatake |first7=Takahiro |last8=Konishi |first8=Kana |last9=Ohno |first9=Harumi |last10=Tanisawa |first10=Kumpei |last11=Mohsen |first11=Attayeb |last12=Chen |first12=Yi-An |last13=Kawashima |first13=Hitoshi |last14=Natsume-Kitatani |first14=Yayoi |last15=Oka |first15=Yoshimasa |last16=Shimizu |first16=Hidenori |last17=Furuta |first17=Mari |last18=Tojima |first18=Yoko |last19=Sawane |first19=Kento |last20=Saika |first20=Azusa |last21=Kondo |first21=Saki |last22=Yonejima |first22=Yasunori |last23=Takeyama |first23=Haruko |last24=Matsutani |first24=Akira |last25=Mizuguchi |first25=Kenji |last26=Miyachi |first26=Motohiko |last27=Kunisawa |first27=Jun |title=Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota |journal=Nature Communications |pages=4477 |language=en |doi=10.1038/s41467-022-32015-7 |date=18 August 2022|volume=13 |issue=1 |pmid=35982037 |pmc=9388534 |bibcode=2022NatCo..13.4477H }}
B. wexlerae has also shown to be positively associated with children with higher cognitive function scores.{{Cite journal |last1=Bonham |first1=Kevin S. |last2=Fahur Bottino |first2=Guilherme |last3=McCann |first3=Shelley Hoeft |last4=Beauchemin |first4=Jennifer |last5=Weisse |first5=Elizabeth |last6=Barry |first6=Fatoumata |last7=Cano Lorente |first7=Rosa |last8=The RESONANCE Consortium |last9=Huttenhower |first9=Curtis |last10=Bruchhage |first10=Muriel |last11=D’Sa |first11=Viren |last12=Deoni |first12=Sean |last13=Klepac-Ceraj |first13=Vanja |date=2023-12-22 |title=Gut-resident microorganisms and their genes are associated with cognition and neuroanatomy in children |journal=Science Advances |language=en |volume=9 |issue=51 |pages=eadi0497 |doi=10.1126/sciadv.adi0497 |issn=2375-2548 |pmc=10745691 |pmid=38134274|bibcode=2023SciA....9I.497B }}