Blue nevus

{{short description|Type of melanocytic tumor}}

{{Infobox medical condition (new)

| name = Blue nevus

| synonyms = Blue neuronevus, dermal melanocytoma, nevus coeruleus, nevus bleu

| image = Blue Nevus (crop).jpg

| width = 150

| caption = Blue nevus

| pronounce =

| field = Dermatology

| symptoms = Single well-defined blue-black bump| complications = Rarely malignant transformation

| onset =

| duration =

| types = Dendritic, cellular

| causes = Unclear

| risks =

| diagnosis = Visualisation, dermoscopy

| differential = Dermatofibroma, melanoma{{MeshName|Blue+Nevi}}

| prevention =

| treatment = Monitoring, excision

| medication =

| prognosis = Good

| frequency = Female>male

| deaths =

}}

A blue nevus is a type of coloured mole, typically a single well-defined blue-black bump.{{cite book |author=Rapini, Ronald P. |author2=Bolognia, Jean L. |author3=Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages=1722 |isbn=978-1-4160-2999-1 }}{{cite book|last=Johnstone |first=Ronald B.|title=Weedon's Skin Pathology Essentials |url=https://books.google.com/books?id=NTE_DAAAQBAJ|year=2017|publisher=Elsevier |isbn=978-0-7020-6830-0|edition=2nd|page=545|chapter=32. Lentigines and melanomas}}

The blue colour is caused by the pigment being deep in the skin.{{cite web |title=Blue naevus |url=https://dermnetnz.org/topics/blue-naevus |website=dermnetnz.org |access-date=21 October 2021 |language=en}}

Diagnosis is by visualisation and dermoscopy. A biopsy is sometimes performed, or the whole lesion surgically removed.{{cite journal |last1=Austad |first1=Steve S. |last2=Athalye |first2=Leela |title=Blue Nevus |journal=StatPearls |date=2021 |url=https://www.ncbi.nlm.nih.gov/books/NBK549774/ |publisher=StatPearls Publishing|pmid=31747181 }} The outcome is generally good but there is a small chance of cancerous transformation. Differential diagnosis includes dermatofibroma and melanoma.

Blue nevi are more common in females than males. It was first studied in 1906 by Tièche, a student of Josef Jadassohn.{{cite journal |last1=Sreeremya |first1=S. |title=Blue Nevus |journal=International Journal of Molecular Biotechnology |date=17 April 2018 |volume=4 |issue=1 |pages=1–4 |doi=10.37628/ijmb.v4i1.255 |doi-broken-date=1 November 2024 |url=http://biotech.journalspub.info/?journal=IJMB&page=article&op=view&path%5B%5D=255 |language=en}}

Classification

Blue nevi may be divided into the following types:{{cite book |author=James, William D. |author2=Berger, Timothy G. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |year=2006 |isbn=0-7216-2921-0 |display-authors=etal}}{{rp|701}}

  • A patch blue nevus (also known as an "acquired dermal melanocytosis", and "dermal melanocyte hamartoma") is a cutaneous condition characterized by a diffusely gray-blue area that may have superimposed darker macules.
  • A blue nevus of Jadassohn–Tièche (also known as a "common blue nevus", and "nevus ceruleus") is a cutaneous condition characterized by a steel-blue papule or nodule.{{rp|701}}
  • A cellular blue nevus is a cutaneous condition characterized by large, firm, blue or blue-black nodules.{{rp|701}}
  • An epithelioid blue nevus is a cutaneous condition most commonly seen in patients with the Carney complex.{{rp|701}}
  • A deep penetrating nevus is a type of benign melanocytic skin tumor characterized, as its name suggests, by penetration into the deep dermis and/or subcutis. Smudged chromatic is a typical finding. In some cases mitotic figures or atypical melanocytic cytology are seen, potentially mimicking a malignant melanoma. Evaluation by an expert skin pathologist is advisable in some cases to help differentiate from invasive melanoma.{{rp|701}}
  • An amelanotic blue nevus (also known as a "hypomelanotic blue nevus") is a cutaneous condition characterized by mild atypia and pleomorphism.{{rp|701}}
  • A malignant blue nevus is a cutaneous condition characterized by a sheet-like growth pattern, mitoses, necrosis, and cellular atypia.{{rp|701}}

blue nevus - intermed mag.jpg|Micrograph of a blue nevus showing the characteristic pigmented melanocytes between bundles of collagen. H&E stain

SkinTumors-408.jpg|Blue nevus

SkinTumors-415.jpg|Cellular blue nevus

SkinTumors-456.jpg|Epithelioid blue nevus

Skin Tumors-P6231211.jpg|Malignant blue nevus

See also

References

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