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Bone morphogenetic protein 8A

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{{Short description|Protein-coding gene in the species Homo sapiens}}

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Bone morphogenetic protein 8A (BMP8A) is a protein that in humans is encoded by the BMP8A gene.{{cite web | title = Entrez Gene: bone morphogenetic protein 8a| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=353500}}

BMP8A is a polypeptide member of the TGFβ superfamily of proteins. It, like other bone morphogenetic proteins (BMPs), is involved in the development of bone and cartilage. BMP8A may be involved in epithelial osteogenesis. It also plays a role in bone homeostasis. It is a disulfide-linked homodimer.

References

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External links

  • {{UCSC gene info|BMP8A}}

Further reading

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  • {{cite journal |vauthors=Davila S, Froeling FE, Tan A |title=New genetic associations detected in a host response study to hepatitis B vaccine. |journal=Genes Immun. |volume=11 |issue= 3 |pages= 232–8 |year= 2010 |pmid= 20237496 |doi= 10.1038/gene.2010.1 |s2cid=11183658 |display-authors=etal|doi-access= }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241|bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
  • {{cite journal |vauthors=Gregory SG, Barlow KF, McLay KE |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 |bibcode=2006Natur.441..315G |display-authors=etal|doi-access=free }}
  • {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}

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{{TGF beta signaling}}

{{TGFβ receptor superfamily modulators}}

{{DEFAULTSORT:Bone Morphogenetic Protein 8a}}

Category:Bone morphogenetic protein

Category:Developmental genes and proteins

Category:TGFβ domain

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