Bonnie Sloane
{{about|cancer researcher|football player|Bonnie Sloan}}
{{short description|Pharmacology professor}}
{{Infobox scientist
| name = Bonnie F. Sloane
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| alma_mater = Rutgers University
| thesis_title = Alterations in lysosomal enzyme activity in rat uterine muscle as affected by the hormonal state of the muscle
| thesis_url = https://www.worldcat.org/oclc/55156883
| thesis_year = 1976
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Bonnie Fiedorek Sloane was a distinguished professor at Wayne State University known for her research on cancer. In 2021 she was elected a fellow of the American Association for the Advancement of Science.
Education and Career
Sloane was born in 1944 in Pittsburgh, Pennsylvania.{{Cite web |title=Bonnie Fiedorek Sloane {{!}} WorldCat.org |url=https://www.worldcat.org/title/4779284649 |access-date=2022-12-31 |website=www.worldcat.org |language=en}} Sloane has a B.S. (1966) and an M.A. (1968) from Duke University (1966). She earned her Ph.D. from Rutgers University in 1976. Following her Ph.D. she did postdoctoral work at the University of Pennsylvania,{{Cite web |date=2013-10-03 |title=Bonnie Sloane |url=https://wayne.edu/people/aa3402 |access-date=2022-12-30 |website=Wayne State University |language=en}} and in 1979 was an assistant professor at the University of Pennsylvania. She then moved to Michigan State University where she was an assistant professor from 1979 until 1980 when she moved to Wayne State University as an assistant professor in the Department of Pharmacology. She was promoted to associate professor in 1984 and to professor in 1989, and in 2005 she was named distinguished professor.
From 1995 until 2015, she served as chair of the Department of Pharmacology, the first woman to serve as chair of a department in the Wayne State University School of Medicine.
From 2009 until 2011, Sloane was president of the Association of Medical Pharmacology, the first woman to serve in this role.{{Cite news |date=2008-09-21 |title=People making news |pages=58 |work=Detroit Free Press |url=https://www.newspapers.com/clip/115479973/detroit-free-press/ |access-date=2022-12-31}}
Research
Sloane is known for her research on cancer, especially breast cancer. Her research has examined cathepsins{{Cite journal |last1=Sloane |first1=Bonnie F. |last2=Dunn |first2=John R. |last3=Honn |first3=Kenneth V. |date=1981-06-05 |title=Lysosomal Cathepsin B: Correlation with Metastatic Potential |url=https://www.science.org/doi/10.1126/science.7233209 |journal=Science |language=en |volume=212 |issue=4499 |pages=1151–1153 |doi=10.1126/science.7233209 |pmid=7233209 |bibcode=1981Sci...212.1151S |s2cid=33974450 |issn=0036-8075}}{{Cite journal |last1=Mohamed |first1=Mona Mostafa |last2=Sloane |first2=Bonnie F. |date=2006 |title=multifunctional enzymes in cancer |url=http://www.nature.com/articles/nrc1949 |journal=Nature Reviews Cancer |language=en |volume=6 |issue=10 |pages=764–775 |doi=10.1038/nrc1949 |pmid=16990854 |s2cid=26463930 |issn=1474-175X}} and proteases{{Cite journal |last1=Koblinski |first1=Jennifer E |last2=Ahram |first2=Mamoun |last3=Sloane |first3=Bonnie F |date=2000-02-15 |title=Unraveling the role of proteases in cancer |url=https://www.sciencedirect.com/science/article/pii/S0009898199002247 |journal=Clinica Chimica Acta |language=en |volume=291 |issue=2 |pages=113–135 |doi=10.1016/S0009-8981(99)00224-7 |pmid=10675719 |issn=0009-8981}} associated with cancer. She has also used imaging with fluorescent probes to track the activity of proteases.{{Cite journal |last1=Blum |first1=Galia |last2=Mullins |first2=Stefanie R |last3=Keren |first3=Kinneret|author3-link=Kinneret Keren |last4=Fonovič |first4=Marko |last5=Jedeszko |first5=Christopher |last6=Rice |first6=Mark J |last7=Sloane |first7=Bonnie F |last8=Bogyo |first8=Matthew |date=2005-09-01 |title=Dynamic imaging of protease activity with fluorescently quenched activity-based probes |url=http://www.nature.com/articles/nchembio728 |journal=Nature Chemical Biology |language=en |volume=1 |issue=4 |pages=203–209 |doi=10.1038/nchembio728 |pmid=16408036 |s2cid=9606676 |issn=1552-4450}}
Selected Publications
- {{Cite journal |last1=Mohamed |first1=Mona Mostafa |author-link=Mona Mostafa Mohamed |last2=Sloane |first2=Bonnie F. |date=2006 |title=Cysteine cathepsins: multifunctional enzymes in cancer |url=http://www.nature.com/articles/nrc1949 |journal=Nature Reviews Cancer |language=en |volume=6 |issue=10 |pages=764–775 |doi=10.1038/nrc1949 |pmid=16990854 |s2cid=26463930 |issn=1474-175X}}
- {{Cite journal |last1=Koblinski |first1=Jennifer E |last2=Ahram |first2=Mamoun |last3=Sloane |first3=Bonnie F |date=2000-02-15 |title=Unraveling the role of proteases in cancer |url=https://www.sciencedirect.com/science/article/pii/S0009898199002247 |journal=Clinica Chimica Acta |language=en |volume=291 |issue=2 |pages=113–135 |doi=10.1016/S0009-8981(99)00224-7 |pmid=10675719 |issn=0009-8981}}
- {{Cite journal |last1=Sloane |first1=Bonnie F. |last2=Dunn |first2=John R. |last3=Honn |first3=Kenneth V. |date=1981-06-05 |title=Lysosomal Cathepsin B: Correlation with Metastatic Potential |url=https://www.science.org/doi/10.1126/science.7233209 |journal=Science |language=en |volume=212 |issue=4499 |pages=1151–1153 |doi=10.1126/science.7233209 |pmid=7233209 |bibcode=1981Sci...212.1151S |s2cid=33974450 |issn=0036-8075}}
Awards and Honors
In 1996, Sloane was elected to the Wayne State University Academy of Scholars. In 2021 Sloane was named a fellow of the American Association for the Advancement of Science.{{Cite journal |date=2022-01-28 |title=2021 AAAS Fellows approved by the AAAS Council |url=https://www.science.org/doi/10.1126/science.ada0325 |journal=Science |language=en |volume=375 |issue=6579 |pages=393–397 |doi=10.1126/science.ada0325 |bibcode=2022Sci...375..393. |s2cid=246359998 |issn=0036-8075}}
References
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External links
- {{google scholar id|QK1Ntd8AAAAJ}}
{{Authority control}}
{{DEFAULTSORT:Sloane, Bonnie}}
Category:Fellows of the American Association for the Advancement of Science
Category:Wayne State University faculty
Category:Women medical researchers