Bowenoid papulosis
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Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules on the body of the penis.Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. {{ISBN|0-07-138076-0}}.{{rp|730}}{{cite book |author=James, William D. |author2=Berger, Timothy G. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |year=2006 |isbn=978-0-7216-2921-6 |display-authors=etal}}{{rp|408}} They are associated with human papillomavirus, the causative agent of genital warts.{{cite journal |vauthors=Goorney BP, Polori R |title=A case of bowenoid papulosis of the penis successfully treated with topical imiquimod cream 5% |journal=Int J STD AIDS |volume=15 |issue=12 |pages=833–5 |date=December 2004 |pmid=15601490 |doi= 10.1258/0956462042563774|s2cid=22765485 |url=http://ijsa.rsmjournals.com/cgi/pmidlookup?view=long&pmid=15601490|url-access=subscription }}
The term bowenoid papulosis was coined in 1977 by Kopf and Bart and is named after dermatologist John Templeton Bowen.{{WhoNamedIt|synd|3996}}{{cite journal |vauthors=Kopf AW, Bart RS |title=Tumor conference No. 11: multiple bowenoid papules of the penis: a new entity? |journal=The Journal of Dermatologic Surgery and Oncology |volume=3 |issue=3 |pages=265–9 |year=1977 |pmid=874134 |doi= 10.1111/j.1524-4725.1977.tb00289.x}}{{cite journal |vauthors=Wade TR, Kopf AW, Ackerman AB |title=Bowenoid papulosis of the penis |journal=Cancer |volume=42 |issue=4 |pages=1890–903 |date=October 1978 |pmid=361215 |doi= 10.1002/1097-0142(197810)42:4<1890::AID-CNCR2820420430>3.0.CO;2-C|doi-access=free }}
Signs and symptoms
Bowenoid papulosis is defined by the appearance of one or more reddish-brown papules or plaques in the anogenital region that can last for a few weeks to several years. Although some patients occasionally report itching in relation to affected perianal skin areas, the majority of individuals do not exhibit any symptoms.{{cite book | last=IACOBUZIO-DONAHUE | first=CHRISTINE A. | title=Surgical Pathology of the GI Tract, Liver, Biliary Tract, and Pancreas | chapter=Inflammatory and Neoplastic Disorders of the Anal Canal | publisher=Elsevier | year=2009 | isbn=978-1-4160-4059-0 | doi=10.1016/b978-141604059-0.50031-x | pages=733–761}}
Causes
Although the exact cause of bowenoid papulosis is unknown, immunologic, viral, and chemical factors have all been proposed. There have been multiple occurrences of bowenoid papulosis where HPV DNA was found.{{cite book | last1=Ro | first1=Jae Y. | last2=Kim | first2=Kyu-Rae | last3=Amin | first3=Mahul B. | last4=Ayala | first4=Alberto G. | title=Urologic Surgical Pathology | chapter=Penis and scrotum | publisher=Elsevier | year=2008 | isbn=978-0-323-01970-5 | doi=10.1016/b978-0-323-01970-5.50017-8 | pages=890–950}}
Diagnosis
Bowenoid papulosis diagnosis requires a history, histologic examination, and clinical description of the condition.{{cite book | last=Gross | first=G. | title=Genital Papillomavirus Infections | chapter=Bowenoid Papulosis | publisher=Springer Berlin Heidelberg | publication-place=Berlin, Heidelberg | date=1990 | isbn=978-3-642-75725-9 | doi=10.1007/978-3-642-75723-5_14 | pages=189–207}}
Treatment
Bowenoid papulosis is typically treated with locally destructive or ablative therapies, including 5-fluorouracil, electrocoagulation, cryotherapy, and surgical excision or razor excision. Imiquimod has also been applied with good results.{{cite book | last=Weedon | first=David | title=Weedon's Skin Pathology | chapter=Viral diseases | publisher=Elsevier | year=2010 | isbn=978-0-7020-3485-5 | doi=10.1016/b978-0-7020-3485-5.00027-9 | page=607–631.e22}}
See also
References
{{Reflist}}
Further reading
- {{cite journal | last1=Patterson | first1=James W. | last2=Kao | first2=Grace F. | last3=Graham | first3=James H. | last4=Helwig | first4=Elson B. | title=Bowenoid papulosis: A clinicopathologic study with ultrastructural observations | journal=Cancer | volume=57 | issue=4 | date=1986-02-15 | issn=0008-543X | doi=10.1002/1097-0142(19860215)57:4<823::AID-CNCR2820570424>3.0.CO;2-3 | pages=823–836 | pmid=3002589 | ref=none}}
- {{cite journal | last1=Nayak | first1=Sudhir U. K. | last2=Shenoi | first2=Shrutakirthi D. | last3=Bhat | first3=Shaila T. | last4=Shivamurthy | first4=Archana | title=Bowenoid papulosis | journal=Indian Journal of Sexually Transmitted Diseases and AIDS | publisher=Wolters Kluwer -- Medknow Publications | volume=36 | issue=2 | date=2024-03-14 | pages=223–225 | pmid=26692627 | doi=10.4103/0253-7184.167196 | doi-access=free | pmc=4660577 | ref=none}}
External links
- [https://dermnetnz.org/topics/bowenoid-papulosis DermNet]
- [https://www.pathologyoutlines.com/topic/penscrotumbowenoid.html Pathology Outlines]
{{Medical resources
| ICD11 = {{ICD11|2E64.2}}
| ICD10 = {{ICD10|D07.4}}
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| DiseasesDB = 33257
| SNOMED CT = 402913004
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| eMedicineTopic = 1131696
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| NORD = bowenoid-papulosis
| GARDNum = 5951
| GARDName = Bowenoid papulosis
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{{Viral cutaneous conditions}}
{{Male genital neoplasia}}
{{Skin tumors, epidermis}}
Category:Epidermal nevi, neoplasms, and cysts