Brefonalol

{{Chembox

| ImageFile = Brefanolol.svg

| ImageSize = 200px

| ImageAlt =

| IUPACName = 6-[1-Hydroxy-2-[(2-methyl-4-phenylbutan-2-yl)amino]ethyl]-3,4-dihydro-1H-quinolin-2-one

| OtherNames = Brefanolol

|Section1={{Chembox Identifiers

| CASNo = 104051-20-9

| CASNo_Ref = {{cascite|correct|CAS}}

| UNII = DVO6SSG9S3

| UNII_Ref = {{fdacite|correct|FDA}}

| PubChem = 65880

| ChemSpiderID = 59289

| ChEMBL = 1742432

| InChI = 1/C22H28N2O2/c1-22(2,13-12-16-6-4-3-5-7-16)23-15-20(25)18-8-10-19-17(14-18)9-11-21(26)24-19/h3-8,10,14,20,23,25H,9,11-13,15H2,1-2H3,(H,24,26)

| InChIKey = YYUZPBGIBVJYSI-UHFFFAOYAN

| StdInChI = 1S/C22H28N2O2/c1-22(2,13-12-16-6-4-3-5-7-16)23-15-20(25)18-8-10-19-17(14-18)9-11-21(26)24-19/h3-8,10,14,20,23,25H,9,11-13,15H2,1-2H3,(H,24,26)

| StdInChIKey = YYUZPBGIBVJYSI-UHFFFAOYSA-N

| SMILES = CC(C)(CCC1=CC=CC=C1)NCC(C2=CC3=C(C=C2)NC(=O)CC3)O}}

|Section2={{Chembox Properties

| C=22 | H=28 | N=2 | O=2

| Appearance =

| Density =

| MeltingPt =

| BoilingPt =

| Solubility = }}

|Section3={{Chembox Hazards

| MainHazards =

| FlashPt =

| AutoignitionPt = }}

}}

Brefonalol is a beta-adrenergic antagonist that reduces heart frequency and blood pressure and dilates blood vessels. It has been studied in around 1990,{{cite journal|pmid=1696669|year=1990|last1=Halabi|first1=A|last2=Endell|first2=W|last3=Halabi|first3=I|last4=Kirch|first4=W|title=Hemodynamic effects of brefanolol and propranolol assessed by noninvasive methods in patients with arterial hypertension|volume=16|issue=1|pages=81–6|journal=Journal of Cardiovascular Pharmacology|doi=10.1097/00005344-199007000-00011|s2cid=41692901|doi-access=free}} but is not known to be marketed {{as of|2021|lc=on}}.