Bulbus cordis

In the early tubular heart, the bulbus cordis is the major outflow pathway.{{Citation|last=Carlson|first=Bruce M.|title=Development of the Heart|date=2014|url=http://www.sciencedirect.com/science/article/pii/B978012801238305460X|work=Reference Module in Biomedical Sciences|publisher=Elsevier|language=en|isbn=978-0-12-801238-3|access-date=2021-01-05}} It receives blood from the primitive ventricle, and passes it to the truncus arteriosus.{{Citation|last1=De Iuliis|first1=Gerardo|title=Chapter 6 – The Frog|date=2011-01-01|url=http://www.sciencedirect.com/science/article/pii/B9780123750600000061|work=The Dissection of Vertebrates |edition=2nd|pages=127–145|editor-last=De Iuliis|editor-first=Gerardo|place=Boston|publisher=Academic Press|language=en|isbn=978-0-12-375060-0|access-date=2021-01-05|last2=Pulerà|first2=Dino|editor2-last=Pulerà|editor2-first=Dino}} After heart looping, it is located slightly to the left of the ventricle.

{{Further|Heart development}}

The early bulbus cordis is formed by the fifth week of development.{{Citation|last=Belmont|first=John W.|title=Chapter 33 – Genetic and Developmental Basis of Congenital Cardiovascular Malformations|date=2015|url=http://www.sciencedirect.com/science/article/pii/B9780124059450000338|work=Principles of Developmental Genetics|edition= 2nd |pages=607–633|editor-last=Moody|editor-first=Sally A.|place=Oxford|publisher=Academic Press|language=en|isbn=978-0-12-405945-0|access-date=2021-01-05}} The truncus arteriosus is derived from it later.

The adjacent walls of the bulbus cordis and ventricle approximate, fuse, and finally disappear, and the bulbus cordis now communicates freely with the right ventricle, while the junction of the bulbus with the truncus arteriosus is brought directly ventral to and applied to the atrial canal.

By the upgrowth of the ventricular septum the bulbus cordis is separated from the left ventricle, but remains an integral part of the right ventricle, of which it forms the infundibulum.

Together, the bulbus cordis and the primitive ventricle give rise to the ventricles of the formed heart.

The bulbus cordis is shared in the development of many animals, including frogs and fish.{{Citation|last1=Zaccone|first1=G.|title=Design and Physiology of the Heart {{!}} Intracardiac Neurons and Neurotransmitters in Fish|date=2011|url=http://www.sciencedirect.com/science/article/pii/B9780123745538002276|encyclopedia=Encyclopedia of Fish Physiology|pages=1067–1072|editor-last=Farrell|editor-first=Anthony P.|place=San Diego|publisher=Academic Press|language=en|isbn=978-0-08-092323-9|access-date=2021-01-05|last2=Marino|first2=F.|last3=Zaccone|first3=D.}}

File:Gray460.png|Head of chick embryo of about thirty-eight hours' incubation, viewed from the ventral surface. X 26

File:Gray461.png|Diagram to illustrate the simple tubular condition of the heart.

File:Gray462.png|Heart of human embryo of about fourteen days.

File:Gray977.png|Human embryo about fifteen days old. Brain and heart represented from right side. Digestive tube and yolk sac in median section.

{{Gray's}}

{{reflist}}

• {{EmbryologyTemple|Heart98/heart97b/sld023}}
• {{EmbryologyUNC|cardev|017}}
• {{LoyolaMedEd|GrossAnatomy/thorax0/Heart_Development/AtrioVent.html}}
• {{cite book |title= Cardiac development |last= Kirby|first= Margaret L.|year= 2007|publisher= Oxford University Press |isbn= 978-0-19-517819-7|page= 119|url= https://books.google.com/books?id=fjhCQ-QbtbsC|access-date=20 April 2011}}

{{Development of circulatory system}}

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Category:Embryology of cardiovascular system

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