Busselton Health Study
{{short description|Long-term health study of Busselton residents}}
{{Use dmy dates|date=November 2019}}
__NOTOC__
The Busselton Health Study is a long-term, on-going health cohort study of residents of the Western Australian city of Busselton. Over 20,000 Busselton residents have participated in surveys concerning such health topics as cardiovascular disease, pulmonary function, diabetes, and cancer, resulting in over 400 publications.{{cite web|url=http://bpmri.org.au/research/research-publications.html|title=Research Publications|date=2 May 2014 |publisher=Busselton Population Medical Research Institute|accessdate=28 July 2019}}{{cite web|url=http://bpmri.org.au/research/key-projects-studies/busselton-health-study-2.html|title=Key Projects & studies: Busselton Health Study|date=13 May 2014 |publisher=Busselton Population Medical Research Institute|accessdate=28 July 2019}} The program was initiated by Kevin Cullen, a local general practitioner, and is administered by the Busselton Population Medical Research Institute, which was established in 2000 as the Busselton Population Medical Research Foundation,{{cite web|url=http://bpmri.org.au/about-us/history.html|title=History|date=2 May 2014 |publisher=Busselton Population Medical Research Institute|accessdate=30 July 2019}} and the School of Population and Global Health, University of Western Australia.{{cite web|url=http://www.sph.uwa.edu.au/community/busselton_health_study|title=Busselton Health Study|publisher=University of Western Australia|accessdate=30 July 2019}} Data from the study was used in a 1996 paper in Nature showing some of the first genetic links to asthma, along with a 1999 paper in the New England Journal of Medicine that was the first to describe the impact of the newly discovered HFE gene causing HFE hereditary haemochromatosis on a population with normal rates of symptoms.{{cite web|url=http://bpmri.org.au/pdfs/news04.pdf|title=Newsletter Vol 1 Issue 1|publisher=Busselton Population Medical Research Foundation|date=October 2004|accessdate=30 July 2019}}{{Cite journal |vauthors=Daniels SE, Bhattacharrya S, James A, etal |title=A genome-wide search for quantitative trait loci underlying asthma. |journal=Nature |volume=383 |issue= 6597 |pages= 247–50 |year= 1996 |pmid= 8805698 |doi= 10.1038/383247a0 |bibcode=1996Natur.383..247D |s2cid=22256638 }}{{cite journal |vauthors=Olynyk J, Cullen D, Aquilia S, Rossi E, Summerville L, Powell L |title=A population-based study of the clinical expression of the hemochromatosis gene |journal=New England Journal of Medicine|volume=341 |issue=10 |pages=718–24 |year=1999 |pmid=10471457 |doi=10.1056/NEJM199909023411002|url=http://researchrepository.murdoch.edu.au/id/eprint/18788/1/population_based_study.pdf }}
Projects
The Busselton Health Survey has included the following projects:
- 1966, 1969, 1972, 1975, 1978, and 1981: Cross-sectional comprehensive surveys of all adults on the Electoral roll (3,400–4,000 participants){{cite web|url=http://bpmri.org.au/research/key-projects-studies/busselton-health-study-2/busselton-health-study-past-projects.html|title=Past projects|date=14 May 2014 |publisher=Busselton Population Medical Research Institute|accessdate=30 July 2019}}
- 1967, 1970, 1973, 1977, and 1983: Cross-sectional comprehensive surveys of school students (high-school only in 1977, in which there were 556 participants; about 1,600 in all other years)
- 1987: Cross-sectional comprehensive surveys of all people aged over 65 (1,120 participants)
- 1990: Cross-sectional respiratory questionnaire of all adults on the electoral roll (3,800 participants)
- 1992: Family asthma survey (250 families with two parents and two children)
- 1994–1995: Followup of all participants in cross-sectional surveys from 1966 to 1983 (5,715 participants)
- 2005–2008: Survey of the changing prevalence of asthma and Chronic obstructive pulmonary disease (over 2,900 adults and 1,500 children)
- 2007–present: The Prevalence of Sleep Disordered Breathing
- 2007–2008: Participated in the international Burden of obstructive lung disease study (more than 600 participants aged over 40){{cite journal|title=Respiratory symptoms and illness in older Australians: the Burden of Obstructive Lung Disease (BOLD) study|vauthors=Toelle B, Xuan W, Bird T, etal|journal=The Medical Journal of Australia|volume=198|issue=3|year=2013|pages=144–148|doi=10.5694/mja11.11640|pmid=23418694|s2cid=3941694 |doi-access=}}
- 2008–2010: Busselton Diabetes Study, based on Fremantle Diabetes Study (200 people with diabetes and 200 matched controls
- 2010–2021: Busselton Healthy Ageing Study (over 5,100 people born between 1946 and 1964){{cite web|url=http://bpmri.org.au/research/key-projects-studies/busselton-health-study-2.html|title=Current studies & projects|date=13 May 2014 |publisher=Busselton Population Medical Research Institute|accessdate=30 July 2019}}
- 2019–2023: Busselton Respiratory Study (aiming to recruit over 3,000 adults)
See also
References
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