C8 complex

{{Short description|Protein involved in the complement system}}

File:3OJY.png

Complement component 8 is a protein involved in the complement system. It is part of the membrane attack complex (MAC).

A hereditary deficiency of C8 can result in increased susceptibility to Neisseria infections, such as meningitis and gonorrhea.

Image:Formowanie MAC.svg

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{{protein

| Name = complement component 8, alpha polypeptide

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| image =

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| HGNCid = 1352

| Symbol = C8A

| AltSymbols =

| EntrezGene = 731

| OMIM = 120950

| RefSeq = NM_000562

| UniProt = P07357

| PDB =

| ECnumber =

| Chromosome = 1

| Arm = p

| Band = 36.2

| LocusSupplementaryData = -22.1

}}

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{{protein

| Name = complement component 8, beta polypeptide

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| HGNCid = 1353

| Symbol = C8B

| AltSymbols =

| EntrezGene = 732

| OMIM = 1209660

| RefSeq = NM_000066

| UniProt = P073o58

| PDB =

| ECnumber =

| Chromosome = 1

| Arm = p

| Band = 36.2

| LocusSupplementaryData = -22.1

}}

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{{protein

| Name = complement component 8, gamma polypeptide

| caption =

| image =

| width =

| HGNCid = 1354

| Symbol = C8G

| AltSymbols =

| EntrezGene = 733

| OMIM = 120930

| RefSeq = NM_000606

| UniProt = P07360

| PDB =

| ECnumber =

| Chromosome = 9

| Arm = q

| Band = 34.3

| LocusSupplementaryData =

}}

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