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CCDC88A

{{Short description|Protein-coding gene in humans}}

{{Infobox_gene}}

Girdin is a protein that in humans is encoded by the CCDC88A gene.{{cite journal | vauthors = Le-Niculescu H, Niesman I, Fischer T, DeVries L, Farquhar MG | title = Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles | journal = J Biol Chem | volume = 280 | issue = 23 | pages = 22012–20 |date=Jun 2005 | pmid = 15749703 | doi = 10.1074/jbc.M501833200 | doi-access = free }}{{cite journal | vauthors = Anai M, Shojima N, Katagiri H, Ogihara T, Sakoda H, Onishi Y, Ono H, Fujishiro M, Fukushima Y, Horike N, Viana A, Kikuchi M, Noguchi N, Takahashi S, Takata K, Oka Y, Uchijima Y, Kurihara H, Asano T | title = A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis | journal = J Biol Chem | volume = 280 | issue = 18 | pages = 18525–35 |date=May 2005 | pmid = 15753085 | doi = 10.1074/jbc.M500586200 | doi-access = free }}{{cite web | title = Entrez Gene: KIAA1212 KIAA1212| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55704}} Although its cellular function are not fully elucidated, it has been associated with glioma.{{Cite journal | url=https://pubmed.ncbi.nlm.nih.gov/25060559/ | pmid=25060559 | year=2014 | last1=Gu | first1=F. | last2=Wang | first2=L. | last3=He | first3=J. | last4=Liu | first4=X. | last5=Zhang | first5=H. | last6=Li | first6=W. | last7=Fu | first7=L. | last8=Ma | first8=Y. | title=Girdin, an actin-binding protein, is critical for migration, adhesion, and invasion of human glioblastoma cells | journal=Journal of Neurochemistry | volume=131 | issue=4 | pages=457–469 | doi=10.1111/jnc.12831 | s2cid=206090300 }}

References

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External links

  • [https://web.archive.org/web/20091111180258/http://www.schizophreniaforum.org/new/detail.asp?id=1545 DISC1 Players Gird For Adult Neurodevelopment] - Schizophrenia Research Forum, 8 oct 2009
  • {{UCSC gene info|CCDC88A}}

Further reading

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  • {{cite journal | vauthors=Kitamura T, Asai N, Enomoto A |title=Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin. |journal=Nat. Cell Biol. |volume=10 |issue= 3 |pages= 329–37 |year= 2008 |pmid= 18264090 |doi= 10.1038/ncb1695 |s2cid=23157573 |display-authors=etal}}
  • {{cite journal | vauthors=Enomoto A, Murakami H, Asai N |title=Akt/PKB regulates actin organization and cell motility via Girdin/APE. |journal=Dev. Cell |volume=9 |issue= 3 |pages= 389–402 |year= 2005 |pmid= 16139227 |doi= 10.1016/j.devcel.2005.08.001 |display-authors=etal|doi-access=free }}
  • {{cite journal | vauthors=Simpson F, Martin S, Evans TM |title=A novel hook-related protein family and the characterization of hook-related protein 1. |journal=Traffic |volume=6 |issue= 6 |pages= 442–58 |year= 2005 |pmid= 15882442 |doi= 10.1111/j.1600-0854.2005.00289.x |s2cid=25389776 |display-authors=etal|doi-access=free }}
  • {{cite journal | vauthors=Ballif BA, Villén J, Beausoleil SA |title=Phosphoproteomic analysis of the developing mouse brain. |journal=Mol. Cell. Proteomics |volume=3 |issue= 11 |pages= 1093–101 |year= 2005 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200 |display-authors=etal|doi-access=free }}
  • {{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
  • {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
  • {{cite journal | vauthors=Nagase T, Ishikawa K, Kikuno R |title=Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro |journal=DNA Res. |volume=6 |issue= 5 |pages= 337–45 |year= 2000 |pmid= 10574462 |doi=10.1093/dnares/6.5.337 |display-authors=etal|doi-access=free }}

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