CDC2L2
{{Short description|Protein-coding gene in humans}}
{{Infobox_gene}}
PITSLRE serine/threonine-protein kinase CDC2L2 is an enzyme that in humans is encoded by the CDC2L2 gene.{{cite journal | vauthors = Lahti JM, Valentine M, Xiang J, Jones B, Amann J, Grenet J, Richmond G, Look AT, Kidd VJ | title = Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma | journal = Nature Genetics | volume = 7 | issue = 3 | pages = 370–5 | date = July 1994 | pmid = 7920654 | doi = 10.1038/ng0794-370 | s2cid = 2065302 }}{{cite journal | vauthors = Gururajan R, Lahti JM, Grenet J, Easton J, Gruber I, Ambros PF, Kidd VJ | title = Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2 | journal = Genome Research | volume = 8 | issue = 9 | pages = 929–39 | date = September 1998 | pmid = 9750192 | pmc = 310781 | doi = 10.1101/gr.8.9.929 }}{{cite web | title = Entrez Gene: LOC728642 similar to cell division cycle 2-like 1 (PITSLRE proteins) isoform 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=728642}}
References
{{reflist}}
External links
- {{UCSC gene info|CDK11A}}
Further reading
{{refbegin | 2}}
- {{cite journal | vauthors = Eipers PG, Lahti JM, Kidd VJ | title = Structure and expression of the human p58clk-1 protein kinase chromosomal gene | journal = Genomics | volume = 13 | issue = 3 | pages = 613–21 | date = July 1992 | pmid = 1639388 | doi = 10.1016/0888-7543(92)90132-C }}
- {{cite journal | vauthors = Eipers PG, Barnoski BL, Han J, Carroll AJ, Kidd VJ | title = Localization of the expressed human p58 protein kinase chromosomal gene to chromosome 1p36 and a highly related sequence to chromosome 15 | journal = Genomics | volume = 11 | issue = 3 | pages = 621–9 | date = November 1991 | pmid = 1774066 | doi = 10.1016/0888-7543(91)90069-Q }}
- {{cite journal | vauthors = Bunnell BA, Heath LS, Adams DE, Lahti JM, Kidd VJ | title = Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 87 | issue = 19 | pages = 7467–71 | date = October 1990 | pmid = 2217177 | pmc = 54768 | doi = 10.1073/pnas.87.19.7467 | bibcode = 1990PNAS...87.7467B | doi-access = free }}
- {{cite journal | vauthors = White PS, Maris JM, Beltinger C, Sulman E, Marshall HN, Fujimori M, Kaufman BA, Biegel JA, Allen C, Hilliard C, Valentine MB, Look AT, Enomoto H, Sakiyama S, Brodeur GM | title = A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 92 | issue = 12 | pages = 5520–4 | date = June 1995 | pmid = 7777541 | pmc = 41727 | doi = 10.1073/pnas.92.12.5520 | bibcode = 1995PNAS...92.5520W | doi-access = free }}
- {{cite journal | vauthors = Xiang J, Lahti JM, Grenet J, Easton J, Kidd VJ | title = Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms | journal = The Journal of Biological Chemistry | volume = 269 | issue = 22 | pages = 15786–15794 | date = June 1994 | doi = 10.1016/S0021-9258(17)40749-6 | pmid = 8195233 | doi-access = free }}
- {{cite journal | vauthors = Beyaert R, Kidd VJ, Cornelis S, Van de Craen M, Denecker G, Lahti JM, Gururajan R, Vandenabeele P, Fiers W | title = Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor | journal = The Journal of Biological Chemistry | volume = 272 | issue = 18 | pages = 11694–7 | date = May 1997 | pmid = 9115219 | doi = 10.1074/jbc.272.18.11694 | doi-access = free }}
- {{cite journal | vauthors = Loyer P, Trembley JH, Lahti JM, Kidd VJ | title = The RNP protein, RNPS1, associates with specific isoforms of the p34cdc2-related PITSLRE protein kinase in vivo | journal = Journal of Cell Science | volume = 111 ( Pt 11) | issue = 11 | pages = 1495–506 | date = June 1998 | doi = 10.1242/jcs.111.11.1495 | pmid = 9580558 }}
- {{cite journal | vauthors = Tang D, Gururajan R, Kidd VJ | title = Phosphorylation of PITSLRE p110 isoforms accompanies their processing by caspases during Fas-mediated cell death | journal = The Journal of Biological Chemistry | volume = 273 | issue = 26 | pages = 16601–7 | date = June 1998 | pmid = 9632733 | doi = 10.1074/jbc.273.26.16601 | doi-access = free }}
- {{cite journal | vauthors = Gururajan R, Grenet J, Lahti JM, Kidd VJ | title = Isolation and characterization of two novel metalloproteinase genes linked to the Cdc2L locus on human chromosome 1p36.3 | journal = Genomics | volume = 52 | issue = 1 | pages = 101–6 | date = August 1998 | pmid = 9740677 | doi = 10.1006/geno.1998.5401 }}
- {{cite journal | vauthors = Cornelis S, Bruynooghe Y, Denecker G, Van Huffel S, Tinton S, Beyaert R | title = Identification and characterization of a novel cell cycle-regulated internal ribosome entry site | journal = Molecular Cell | volume = 5 | issue = 4 | pages = 597–605 | date = April 2000 | pmid = 10882096 | doi = 10.1016/S1097-2765(00)80239-7 | doi-access = free }}
- {{cite journal | vauthors = Zhang SW, Xu SL, Cai MM, Yan J, Zhu XY, Hu Y, Gu JX | title = Effect of p58GTA on beta-1,4-galactosyltransferase 1 activity and cell-cycle in human hepatocarcinoma cells | journal = Molecular and Cellular Biochemistry | volume = 221 | issue = 1–2 | pages = 161–8 | date = May 2001 | pmid = 11506180 | doi = 10.1023/A:1010932211745 | s2cid = 25573580 }}
- {{cite journal | vauthors = Berke JD, Sgambato V, Zhu PP, Lavoie B, Vincent M, Krause M, Hyman SE | title = Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin | journal = Neuron | volume = 32 | issue = 2 | pages = 277–87 | date = October 2001 | pmid = 11683997 | doi = 10.1016/S0896-6273(01)00465-2 | s2cid = 14486999 | doi-access = free }}
- {{cite journal | vauthors = Dickinson LA, Edgar AJ, Ehley J, Gottesfeld JM | title = Cyclin L is an RS domain protein involved in pre-mRNA splicing | journal = The Journal of Biological Chemistry | volume = 277 | issue = 28 | pages = 25465–73 | date = July 2002 | pmid = 11980906 | doi = 10.1074/jbc.M202266200 | doi-access = free }}
- {{cite journal | vauthors = Shi J, Feng Y, Goulet AC, Vaillancourt RR, Sachs NA, Hershey JW, Nelson MA | title = The p34cdc2-related cyclin-dependent kinase 11 interacts with the p47 subunit of eukaryotic initiation factor 3 during apoptosis | journal = The Journal of Biological Chemistry | volume = 278 | issue = 7 | pages = 5062–71 | date = February 2003 | pmid = 12446680 | doi = 10.1074/jbc.M206427200 | doi-access = free }}
- {{cite journal | vauthors = Hu D, Mayeda A, Trembley JH, Lahti JM, Kidd VJ | title = CDK11 complexes promote pre-mRNA splicing | journal = The Journal of Biological Chemistry | volume = 278 | issue = 10 | pages = 8623–9 | date = March 2003 | pmid = 12501247 | doi = 10.1074/jbc.M210057200 | doi-access =free }}
- {{cite journal | vauthors = Chen S, Yin X, Zhu X, Yan J, Ji S, Chen C, Cai M, Zhang S, Zong H, Hu Y, Yuan Z, Shen Z, Gu J | title = The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikis | journal = The Journal of Biological Chemistry | volume = 278 | issue = 22 | pages = 20029–36 | date = May 2003 | pmid = 12624090 | doi = 10.1074/jbc.M300818200 | doi-access = free }}
{{refend}}
{{protein-stub}}