CDP-diacylglycerol—serine O-phosphatidyltransferase

{{Short description|Class of enzymes}}

{{infobox enzyme

| Name = CDP-diacylglycerol-serine O-phosphatidyltransferase

| EC_number = 2.7.8.8

| CAS_number = 9068-48-8

| GO_code = 0003882

| image =

| width =

| caption =

}}

In enzymology, a CDP-diacylglycerol—serine O-phosphatidyltransferase ({{EC number|2.7.8.8}}) is an enzyme that catalyzes the chemical reaction

:CDP-diacylglycerol + L-serine $\backslash rightleftharpoons$ CMP + (3-sn-phosphatidyl)-L-serine

Thus, the two substrates of this enzyme are CDP-diacylglycerol and L-serine, whereas its two products are CMP and (3-sn-phosphatidyl)-L-serine.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-diacylglycerol:L-serine 3-sn-phosphatidyltransferase. Other names in common use include phosphatidylserine synthase, CDPdiglyceride-serine O-phosphatidyltransferase, PS synthase, cytidine 5'-diphospho-1,2-diacyl-sn-glycerol, (CDPdiglyceride):L-serine O-phosphatidyltransferase, phosphatidylserine synthetase, CDP-diacylglycerol-L-serine O-phosphatidyltransferase, cytidine diphosphoglyceride-serine O-phosphatidyltransferase, CDP-diglyceride-L-serine phosphatidyltransferase, CDP-diglyceride:serine phosphatidyltransferase, cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine, O-phosphatidyltransferase, and CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase. This enzyme participates in glycine, serine and threonine metabolism and glycerophospholipid metabolism.