CEP152
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Centrosomal protein of 152 kDa, also known as Cep152, is a protein that in humans is encoded by the CEP152 gene.{{cite web | title = Entrez Gene: centrosomal protein 152kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22995}} It is the ortholog of the Drosophila melanogaster gene asterless (asl) and both are required for centriole duplication.{{cite journal |vauthors=Blachon S, Gopalakrishnan J, Omori Y, Polyanovsky A, Church A, Nicastro D, Malicki J, Avidor-Reiss T | title = Drosophila asterless and vertebrate Cep152 Are orthologs essential for centriole duplication | journal = Genetics | volume = 180 | issue = 4 | pages = 2081–94 |date=December 2008 | pmid = 18854586 | pmc = 2600943 | doi = 10.1534/genetics.108.095141 }}
References
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External links
- {{UCSC gene info|CEP152}}
- {{PDBe-KB2|O94986|Centrosomal protein of 152 kDa}}
Further reading
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- {{cite journal |vauthors=Nakayama M, Kikuno R, Ohara O |title=Protein–Protein Interactions Between Large Proteins: Two-Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs |journal=Genome Res. |volume=12 |issue= 11 |pages= 1773–84 |year= 2002 |pmid= 12421765 |pmc=187542 |doi= 10.1101/gr.406902 }}
- {{cite journal |vauthors=Nagase T, Ishikawa K, Suyama M |title=Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro |journal=DNA Res. |volume=5 |issue= 6 |pages= 355–64 |year= 1998 |pmid= 10048485 |doi= 10.1093/dnares/5.6.355|display-authors=etal|doi-access=free }}
- {{cite journal |vauthors=Andersen JS, Wilkinson CJ, Mayor T |title=Proteomic characterization of the human centrosome by protein correlation profiling |journal=Nature |volume=426 |issue= 6966 |pages= 570–4 |year= 2003 |pmid= 14654843 |doi= 10.1038/nature02166 |bibcode=2003Natur.426..570A |s2cid=4427303 |display-authors=etal}}
- {{cite journal |vauthors=Golsteyn RM, Mundt KE, Fry AM, Nigg EA |title=Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function |journal=J. Cell Biol. |volume=129 |issue= 6 |pages= 1617–28 |year= 1995 |pmid= 7790358 |pmc=2291169 |doi=10.1083/jcb.129.6.1617 }}
- {{cite journal |vauthors=Casenghi M, Meraldi P, Weinhart U |title=Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation |journal=Dev. Cell |volume=5 |issue= 1 |pages= 113–25 |year= 2003 |pmid= 12852856 |doi=10.1016/S1534-5807(03)00193-X |display-authors=etal|doi-access=free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |pmc=528928 |doi= 10.1101/gr.2596504 |display-authors=etal}}
- {{cite journal |vauthors=Mayor T, Stierhof YD, Tanaka K |title=The Centrosomal Protein C-Nap1 Is Required for Cell Cycle–Regulated Centrosome Cohesion |journal=J. Cell Biol. |volume=151 |issue= 4 |pages= 837–46 |year= 2000 |pmid= 11076968 |pmc=2169446 |doi=10.1083/jcb.151.4.837 |display-authors=etal}}
- {{cite journal |vauthors=Petretti C, Savoian M, Montembault E |title=The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation |journal=EMBO Rep. |volume=7 |issue= 4 |pages= 418–24 |year= 2006 |pmid= 16462731 |pmc=1456919 |doi= 10.1038/sj.embor.7400639 |display-authors=etal}}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |pmc=139241 |doi= 10.1073/pnas.242603899 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
- {{cite journal |vauthors=Takahashi M, Yamagiwa A, Nishimura T |title=Centrosomal Proteins CG-NAP and Kendrin Provide Microtubule Nucleation Sites by Anchoring γ-Tubulin Ring Complex |journal=Mol. Biol. Cell |volume=13 |issue= 9 |pages= 3235–45 |year= 2002 |pmid= 12221128 |pmc=124155 |doi= 10.1091/mbc.E02-02-0112 |display-authors=etal}}
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{{Centrosome}}
{{gene-15-stub}}