CEP57
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Centrosomal protein of 57 kDa is a protein that in humans is encoded by the CEP57 gene.{{cite journal | vauthors = Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S, Ishikawa K, Kawarabayasi Y, Kotani H | title = Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1 | journal = DNA Res | volume = 2 | issue = 1 | pages = 37–43 |date=Jul 1995 | pmid = 7788527 | doi =10.1093/dnares/2.1.37 |display-authors=etal| doi-access = free }}{{cite web | title = Entrez Gene: CEP57 centrosomal protein 57kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9702}} It is also known as translokin.
Translokin binds basic fibroblast growth factor (FGF2; MIM 134920) and mediates its nuclear translocation and mitogenic activity (Bossard et al., 2003).[supplied by OMIM]{{cite web | title = Entrez Gene: CEP57 centrosomal protein 57kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9702}}
References
{{reflist}}
External links
- {{UCSC gene info|CEP57}}
- [https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/Q86XR8 PDBe-KB] provides an overview of all the structure information available in the PDB for Human Centrosomal protein of 57 kDa
Further reading
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- {{cite journal | vauthors=Hoja MR, Wahlestedt C, Höög C |title=A visual intracellular classification strategy for uncharacterized human proteins. |journal=Exp. Cell Res. |volume=259 |issue= 1 |pages= 239–46 |year= 2000 |pmid= 10942595 |doi= 10.1006/excr.2000.4948 }}
- {{cite journal | vauthors=Nakayama M, Kikuno R, Ohara O |title=Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. |journal=Genome Res. |volume=12 |issue= 11 |pages= 1773–84 |year= 2003 |pmid= 12421765 |doi= 10.1101/gr.406902 | pmc=187542 }}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Bossard C, Laurell H, Van den Berghe L |title=Translokin is an intracellular mediator of FGF-2 trafficking. |journal=Nat. Cell Biol. |volume=5 |issue= 5 |pages= 433–9 |year= 2003 |pmid= 12717444 |doi= 10.1038/ncb979 |s2cid=21792653 |display-authors=etal}}
- {{cite journal | vauthors=Kim YS, Nakanishi G, Oudes AJ |title=Tsp57: a novel gene induced during a specific stage of spermatogenesis. |journal=Biol. Reprod. |volume=70 |issue= 1 |pages= 106–13 |year= 2004 |pmid= 12954732 |doi= 10.1095/biolreprod.103.018465 |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Andersen JS, Wilkinson CJ, Mayor T |title=Proteomic characterization of the human centrosome by protein correlation profiling. |journal=Nature |volume=426 |issue= 6966 |pages= 570–4 |year= 2003 |pmid= 14654843 |doi= 10.1038/nature02166 |bibcode=2003Natur.426..570A |s2cid=4427303 |display-authors=etal}}
- {{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal | vauthors=Ahn J, Chung KS, Kim DU |title=Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus. |journal=J. Biochem. Mol. Biol. |volume=37 |issue= 6 |pages= 741–8 |year= 2005 |pmid= 15607035 |doi= 10.5483/bmbrep.2004.37.6.741|display-authors=etal|doi-access=free }}
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{{centrosome}}
{{gene-11-stub}}