CFHR1
{{Short description|Protein-coding gene in humans}}
{{Infobox_gene}}
Complement factor H-related protein 1 is a protein that in humans is encoded by the CFHR1 gene.{{cite journal | vauthors = Skerka C, Horstmann RD, Zipfel PF | title = Molecular cloning of a human serum protein structurally related to complement factor H | journal = J Biol Chem | volume = 266 | issue = 18 | pages = 12015–20 |date=Jul 1991 | doi = 10.1016/S0021-9258(18)99058-7 | pmid = 1711047 | doi-access = free }}{{cite journal | vauthors = Estaller C, Koistinen V, Schwaeble W, Dierich MP, Weiss EH | title = Cloning of the 1.4-kb mRNA species of human complement factor H reveals a novel member of the short consensus repeat family related to the carboxy terminal of the classical 150-kDa molecule | journal = J Immunol | volume = 146 | issue = 9 | pages = 3190–6 |date=May 1991 | doi = 10.4049/jimmunol.146.9.3190 | pmid = 1826708 | doi-access = free | url = https://epub.ub.uni-muenchen.de/3049/1/021.pdf }}{{cite web | title = Entrez Gene: CFHR1 complement factor H-related 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3078}}
References
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Further reading
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- {{cite journal | vauthors=Zipfel PF, Skerka C |title=Complement factor H and related proteins: an expanding family of complement-regulatory proteins? |journal=Immunol. Today |volume=15 |issue= 3 |pages= 121–6 |year= 1994 |pmid= 8172644 |doi=10.1016/0167-5699(94)90155-4 }}
- {{cite journal | vauthors=Zipfel PF, Jokiranta TS, Hellwage J |title=The factor H protein family. |journal=Immunopharmacology |volume=42 |issue= 1–3 |pages= 53–60 |year= 1999 |pmid= 10408366 |doi=10.1016/S0162-3109(99)00015-6 |display-authors=etal}}
- {{cite journal | vauthors=Timmann C, Leippe M, Horstmann RD |title=Two major serum components antigenically related to complement factor H are different glycosylation forms of a single protein with no factor H-like complement regulatory functions. |journal=J. Immunol. |volume=146 |issue= 4 |pages= 1265–70 |year= 1991 |doi=10.4049/jimmunol.146.4.1265 |pmid= 1825108 |s2cid=37805964 |doi-access=free }}
- {{cite journal | vauthors=Park CT, Wright SD |title=Plasma lipopolysaccharide-binding protein is found associated with a particle containing apolipoprotein A-I, phospholipid, and factor H-related proteins. |journal=J. Biol. Chem. |volume=271 |issue= 30 |pages= 18054–60 |year= 1996 |pmid= 8663389 |doi=10.1074/jbc.271.30.18054 |doi-access=free }}
- {{cite journal | vauthors=Díaz-Guillén MA, Rodríguez de Córdoba S, Heine-Suñer D |title=A radiation hybrid map of complement factor H and factor H-related genes. |journal=Immunogenetics |volume=49 |issue= 6 |pages= 549–52 |year= 1999 |pmid= 10380701 |doi=10.1007/s002510050534 |s2cid=31776506 }}
- {{cite journal | vauthors=Male DA, Ormsby RJ, Ranganathan S |title=Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes. |journal=Mol. Immunol. |volume=37 |issue= 1–2 |pages= 41–52 |year= 2000 |pmid= 10781834 |doi=10.1016/S0161-5890(00)00024-9 |display-authors=etal}}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal | vauthors=Pérez-Caballero D, García-Laorden I, Cortés G |title=Interaction between complement regulators and Streptococcus pyogenes: binding of C4b-binding protein and factor H/factor H-like protein 1 to M18 strains involves two different cell surface molecules. |journal=J. Immunol. |volume=173 |issue= 11 |pages= 6899–904 |year= 2005 |pmid= 15557185 |doi= 10.4049/jimmunol.173.11.6899|display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R |s2cid=4427026 |display-authors=etal}}
- {{cite journal | vauthors=McDowell JV, Lankford J, Stamm L |title=Demonstration of factor H-like protein 1 binding to Treponema denticola, a pathogen associated with periodontal disease in humans. |journal=Infect. Immun. |volume=73 |issue= 11 |pages= 7126–32 |year= 2005 |pmid= 16239506 |doi= 10.1128/IAI.73.11.7126-7132.2005 | pmc=1273895 |display-authors=etal}}
- {{cite journal | vauthors=Liu T, Qian WJ, Gritsenko MA |title=Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. |journal=J. Proteome Res. |volume=4 |issue= 6 |pages= 2070–80 |year= 2006 |pmid= 16335952 |doi= 10.1021/pr0502065 | pmc=1850943 |display-authors=etal}}
- {{cite journal | vauthors=Gregory SG, Barlow KF, McLay KE |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 |bibcode=2006Natur.441..315G |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Zipfel PF, Edey M, Heinen S |title=Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome. |journal=PLOS Genet. |volume=3 |issue= 3 |pages= e41 |year= 2007 |pmid= 17367211 |doi= 10.1371/journal.pgen.0030041 | pmc=1828695 |display-authors=etal |doi-access=free }}
- {{cite journal | vauthors=Haupt K, Kraiczy P, Wallich R |title=Binding of human factor H-related protein 1 to serum-resistant Borrelia burgdorferi is mediated by borrelial complement regulator-acquiring surface proteins. |journal=J. Infect. Dis. |volume=196 |issue= 1 |pages= 124–33 |year= 2007 |pmid= 17538892 |doi= 10.1086/518509 |display-authors=etal|doi-access=free }}
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{{PDB Gallery|geneid=3078}}
External links
- {{UCSC gene info|CFHR1}}
- [https://www.ncbi.nlm.nih.gov/books/NBK1367/ GeneReviews/NCBI/NIH/UW entry on Atypical Hemolytic-Uremic Syndrome]
- [https://www.ncbi.nlm.nih.gov/omim/277400,120700,120920,134370,134371,138470,188040,217030,235400,605336,605337,612922,612923,612924,612925,612926,120700,120920,134370,134371,138470,188040,217030,235400,605336,605337,612922,612923,612924,612925,612926 OMIM entries on Atypical Hemolytic-Uremic Syndrome]
{{gene-1-stub}}