CHRNB3

{{Short description|Protein-coding gene in humans}}

{{Infobox_gene}}

Neuronal acetylcholine receptor subunit beta-3 is a protein that in humans is encoded by the CHRNB3 gene.{{cite journal | vauthors = Anand R, Lindstrom J | title = Chromosomal localization of seven neuronal nicotinic acetylcholine receptor subunit genes in humans | journal = Genomics | volume = 13 | issue = 4 | pages = 962–7 |date=Sep 1992 | pmid = 1505988 | doi =10.1016/0888-7543(92)90008-G }}{{cite web | title = Entrez Gene: CHRNB3 cholinergic receptor, nicotinic, beta 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1142}} This gene has been identified as a candidate for predisposition to tobacco dependence.

See also

References

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Further reading

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  • {{cite journal | vauthors=Green WN, Millar NS |title=Ion-channel assembly. |journal=Trends Neurosci. |volume=18 |issue= 6 |pages= 280–7 |year= 1995 |pmid= 7571003 |doi=10.1016/0166-2236(95)93915-K }}
  • {{cite book | vauthors=Hogg RC, Raggenbass M, Bertrand D |title=Reviews of Physiology, Biochemistry and Pharmacology |chapter=Nicotinic acetylcholine receptors: from structure to brain function |journal=Rev. Physiol. Biochem. Pharmacol. |volume=147 |pages= 1–46 |year= 2003 |pmid= 12783266 |doi= 10.1007/s10254-003-0005-1 | isbn=978-3-540-01365-5 }}
  • {{cite journal | author=Willoughby JJ |title=Molecular cloning of a human neuronal nicotinic acetylcholine receptor beta 3-like subunit |journal=Neurosci. Lett. |volume=155 |issue= 2 |pages= 136–9 |year= 1993 |pmid= 7690916 |doi=10.1016/0304-3940(93)90691-D |name-list-style=vanc| author2=Ninkina NN | author3=Beech MM | display-authors=3 | last4=Latchman | first4=D | last5=Wood | first5=J |s2cid=39225391 }}
  • {{cite journal | vauthors=Koyama K, Sudo K, Nakamura Y |title=Mapping of the human nicotinic acetylcholine receptor beta 3 gene (CHRNB3) within chromosome 8p11.2 |journal=Genomics |volume=21 |issue= 2 |pages= 460–1 |year= 1994 |pmid= 8088849 |doi= 10.1006/geno.1994.1300 }}
  • {{cite journal | author=Elliott KJ |title=Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits |journal=J. Mol. Neurosci. |volume=7 |issue= 3 |pages= 217–28 |year= 1997 |pmid= 8906617 |doi=10.1007/BF02736842 |name-list-style=vanc| author2=Ellis SB | author3=Berckhan KJ | display-authors=3 | last4=Urrutia | first4=Arturo | last5=Chavez-Noriega | first5=Laura E. | last6=Johnson | first6=Edwin C. | last7=Veliçelebi | first7=Gönül | last8=Harpold | first8=Michael M. |s2cid=45737923 }}
  • {{cite journal | vauthors=Groot Kormelink PJ, Luyten WH |title=Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32 |journal=FEBS Lett. |volume=400 |issue= 3 |pages= 309–14 |year= 1997 |pmid= 9009220 |doi=10.1016/S0014-5793(96)01383-X |s2cid=82364119 |doi-access= }}
  • {{cite journal | vauthors=Navaneetham D, Penn A, Howard J, Conti-Fine BM |title=Expression of the alpha 7 subunit of the nicotinic acetylcholine receptor in normal and myasthenic human thymuses |journal=Cell. Mol. Biol. (Noisy-le-grand) |volume=43 |issue= 3 |pages= 433–42 |year= 1997 |pmid= 9193799 }}
  • {{cite journal | vauthors=Groot-Kormelink PJ, Luyten WH, Colquhoun D, Sivilotti LG |title=A reporter mutation approach shows incorporation of the "orphan" subunit beta3 into a functional nicotinic receptor |journal=J. Biol. Chem. |volume=273 |issue= 25 |pages= 15317–20 |year= 1998 |pmid= 9624109 |doi=10.1074/jbc.273.25.15317 |doi-access=free }}
  • {{cite journal | author=Sato KZ |title=Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear leukocytes and leukemic cell lines |journal=Neurosci. Lett. |volume=266 |issue= 1 |pages= 17–20 |year= 1999 |pmid= 10336173 |doi=10.1016/S0304-3940(99)00259-1 |name-list-style=vanc| author2=Fujii T | author3=Watanabe Y | display-authors=3 | last4=Yamada | first4=Shin | last5=Ando | first5=Tsuyoshi | last6=Kazuko | first6=Fujimoto | last7=Kawashima | first7=Koichiro |s2cid=43548155 }}
  • {{cite journal | vauthors=Boorman JP, Groot-Kormelink PJ, Sivilotti LG |title=Stoichiometry of human recombinant neuronal nicotinic receptors containing the β3 subunit expressed in Xenopus oocytes |journal=J. Physiol. |volume=529 Pt 3 |issue= Pt 3|pages= 565–77 |year= 2001 |pmid= 11118490 |doi= 10.1111/j.1469-7793.2000.00565.x| pmc=2270211 }}
  • {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-style=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | author=Boorman JP |title=The effects of beta3 subunit incorporation on the pharmacology and single channel properties of oocyte-expressed human alpha3beta4 neuronal nicotinic receptors |journal=J. Biol. Chem. |volume=278 |issue= 45 |pages= 44033–40 |year= 2004 |pmid= 12912995 |doi= 10.1074/jbc.M211719200 |name-list-style=vanc| author2=Beato M | author3=Groot-Kormelink PJ | display-authors=3 | last4=Broadbent | first4=SD | last5=Sivilotti | first5=LG |doi-access= free}}
  • {{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-style=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}

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