CLCN3

CLCN3 has been shown to interact with PDZK1.{{cite journal | vauthors = Gentzsch M, Cui L, Mengos A, Chang XB, Chen JH, Riordan JR | title = The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins | journal = J. Biol. Chem. | volume = 278 | issue = 8 | pages = 6440–9 | date = Feb 2003 | pmid = 12471024 | doi = 10.1074/jbc.M211050200 | doi-access = free }}

• Chloride channel

{{reflist}}

{{refbegin | 2}}

• {{cite journal | vauthors = Borsani G, Rugarli EI, Taglialatela M, Wong C, Ballabio A | title = Characterization of a human and murine gene (CLCN3) sharing similarities to voltage-gated chloride channels and to a yeast integral membrane protein | journal = Genomics | volume = 27 | issue = 1 | pages = 131–41 | year = 1995 | pmid = 7665160 | doi = 10.1006/geno.1995.1015 }}
• {{cite journal | vauthors = Taine L, Coupry I, Boisseau P, Saura R, Lacombe D, Arveiler B | title = Refined localisation of the voltage-gated chloride channel, CLCN3, to 4q33 | journal = Hum. Genet. | volume = 102 | issue = 2 | pages = 178–81 | year = 1998 | pmid = 9521585 | doi = 10.1007/s004390050673 | s2cid = 22138203 }}
• {{cite journal | vauthors = Shepard AR, Rae JL | title = Ion transporters and receptors in cDNA libraries from lens and cornea epithelia | journal = Curr. Eye Res. | volume = 17 | issue = 7 | pages = 708–19 | year = 1998 | pmid = 9678416 | doi = 10.1080/02713689808951247 }}
• {{cite journal | vauthors = Loo MA, Jensen TJ, Cui L, Hou Y, Chang XB, Riordan JR | title = Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome | journal = EMBO J. | volume = 17 | issue = 23 | pages = 6879–87 | year = 1998 | pmid = 9843494 | pmc = 1171036 | doi = 10.1093/emboj/17.23.6879 }}
• {{cite journal | vauthors = Lamb FS, Clayton GH, Liu BX, Smith RL, Barna TJ, Schutte BC | title = Expression of CLCN voltage-gated chloride channel genes in human blood vessels | journal = J. Mol. Cell. Cardiol. | volume = 31 | issue = 3 | pages = 657–66 | year = 1999 | pmid = 10198195 | doi = 10.1006/jmcc.1998.0901 }}
• {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA cloning using in vitro site-specific recombination | journal = Genome Res. | volume = 10 | issue = 11 | pages = 1788–95 | year = 2000 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }}
• {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Res. | volume = 11 | issue = 3 | pages = 422–35 | year = 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
• {{cite journal | vauthors = Huang P, Liu J, Di A, Robinson NC, Musch MW, Kaetzel MA, Nelson DJ | title = Regulation of human CLC-3 channels by multifunctional Ca2+/calmodulin-dependent protein kinase | journal = J. Biol. Chem. | volume = 276 | issue = 23 | pages = 20093–100 | year = 2001 | pmid = 11274166 | doi = 10.1074/jbc.M009376200 | doi-access = free }}
• {{cite journal | vauthors = Lamb FS, Graeff RW, Clayton GH, Smith RL, Schutte BC, McCray PB | title = Ontogeny of CLCN3 chloride channel gene expression in human pulmonary epithelium | journal = Am. J. Respir. Cell Mol. Biol. | volume = 24 | issue = 4 | pages = 376–81 | year = 2001 | pmid = 11306429 | doi = 10.1165/ajrcmb.24.4.4114 }}
• {{cite journal | vauthors = Ogura T, Furukawa T, Toyozaki T, Yamada K, Zheng YJ, Katayama Y, Nakaya H, Inagaki N | title = ClC-3B, a novel ClC-3 splicing variant that interacts with EBP50 and facilitates expression of CFTR-regulated ORCC | journal = FASEB J. | volume = 16 | issue = 8 | pages = 863–5 | year = 2002 | pmid = 11967229 | doi = 10.1096/fj.01-0845fje | doi-access = free | s2cid = 33470444 }}
• {{cite journal | vauthors = Hermoso M, Satterwhite CM, Andrade YN, Hidalgo J, Wilson SM, Horowitz B, Hume JR | title = ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytes | journal = J. Biol. Chem. | volume = 277 | issue = 42 | pages = 40066–74 | year = 2002 | pmid = 12183454 | doi = 10.1074/jbc.M205132200 | doi-access = free }}
• {{cite journal | vauthors = Gentzsch M, Cui L, Mengos A, Chang XB, Chen JH, Riordan JR | title = The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins | journal = J. Biol. Chem. | volume = 278 | issue = 8 | pages = 6440–9 | year = 2003 | pmid = 12471024 | doi = 10.1074/jbc.M211050200 | doi-access = free }}
• {{cite journal | vauthors = Jin NG, Kim JK, Yang DK, Cho SJ, Kim JM, Koh EJ, Jung HC, So I, Kim KW | title = Fundamental role of ClC-3 in volume-sensitive Cl- channel function and cell volume regulation in AGS cells | journal = Am. J. Physiol. Gastrointest. Liver Physiol. | volume = 285 | issue = 5 | pages = G938-48 | year = 2003 | pmid = 12842831 | doi = 10.1152/ajpgi.00470.2002 | s2cid = 326508 }}
• {{cite journal | vauthors = Olsen ML, Schade S, Lyons SA, Amaral MD, Sontheimer H | title = Expression of voltage-gated chloride channels in human glioma cells | journal = J. Neurosci. | volume = 23 | issue = 13 | pages = 5572–82 | year = 2003 | pmid = 12843258 | doi = 10.1523/JNEUROSCI.23-13-05572.2003| doi-access = free | pmc = 6741216 }}
• {{cite journal | vauthors = Salazar G, Love R, Styers ML, Werner E, Peden A, Rodriguez S, Gearing M, Wainer BH, Faundez V | title = AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells | journal = J. Biol. Chem. | volume = 279 | issue = 24 | pages = 25430–9 | year = 2004 | pmid = 15073168 | doi = 10.1074/jbc.M402331200 | doi-access = free }}
• {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | title = From ORFeome to biology: a functional genomics pipeline | journal = Genome Res. | volume = 14 | issue = 10B | pages = 2136–44 | year = 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }}
• {{cite journal | vauthors = Zhou JG, Ren JL, Qiu QY, He H, Guan YY | title = Regulation of intracellular Cl- concentration through volume-regulated ClC-3 chloride channels in A10 vascular smooth muscle cells | journal = J. Biol. Chem. | volume = 280 | issue = 8 | pages = 7301–8 | year = 2005 | pmid = 15596438 | doi = 10.1074/jbc.M412813200 | doi-access = free }}
• {{cite journal | vauthors = Yeung CH, Barfield JP, Cooper TG | title = Chloride channels in physiological volume regulation of human spermatozoa | journal = Biol. Reprod. | volume = 73 | issue = 5 | pages = 1057–63 | year = 2005 | pmid = 16033995 | doi = 10.1095/biolreprod.105.044123 | doi-access = free }}
• {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | title = The LIFEdb database in 2006 | journal = Nucleic Acids Res. | volume = 34 | issue = Database issue | pages = D415-8 | year = 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }}

{{refend}}

• {{MeshName|CLCN3+protein,+human}}
• {{UCSC gene info|CLCN3}}

{{NLM content}}

{{Ion channels|g4}}

Category:Ion channels

{{gene-4-stub}}