CLEC11A

This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.

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• {{cite journal | vauthors = Hiraoka A, Ohkubo T, Fukuda M | title = Production of human hematopoietic survival and growth factor by a myeloid leukemia cell line (KPB-M15) and placenta as detected by a monoclonal antibody | journal = Cancer Research | volume = 47 | issue = 19 | pages = 5025–30 | date = October 1987 | pmid = 3304620 }}
• {{cite journal | vauthors = Mio H, Kagami N, Yokokawa S, Kawai H, Nakagawa S, Takeuchi K, Sekine S, Hiraoka A | title = Isolation and characterization of a cDNA for human mouse, and rat full-length stem cell growth factor, a new member of C-type lectin superfamily | journal = Biochemical and Biophysical Research Communications | volume = 249 | issue = 1 | pages = 124–30 | date = August 1998 | pmid = 9705843 | doi = 10.1006/bbrc.1998.9073 }}
• {{cite journal | vauthors = Bannwarth S, Giordanengo V, Grosgeorge J, Turc-Carel C, Lefebvre JC | title = Cloning, mapping, and genomic organization of the LSLCL gene, encoding a new lymphocytic secreted mucin-like protein with a C-type lectin domain: A new model of exon shuffling | journal = Genomics | volume = 57 | issue = 2 | pages = 316–7 | date = April 1999 | pmid = 10198175 | doi = 10.1006/geno.1999.5762 }}
• {{cite journal | vauthors = Gehling UM, Ergün S, Schumacher U, Wagener C, Pantel K, Otte M, Schuch G, Schafhausen P, Mende T, Kilic N, Kluge K, Schäfer B, Hossfeld DK, Fiedler W | title = In vitro differentiation of endothelial cells from AC133-positive progenitor cells | journal = Blood | volume = 95 | issue = 10 | pages = 3106–12 | date = May 2000 | pmid = 10807776 | doi = 10.1182/blood.V95.10.3106}}
• {{cite journal | vauthors = Perrin C, Bayle J, Bannwarth S, Michiels JF, Heudier P, Lefebvre JC, Giordanengo V | title = Expression of LSLCL, a new C-type lectin, is closely restricted, in bone marrow, to immature neutrophils | journal = Comptes Rendus de l'Académie des Sciences, Série III | volume = 324 | issue = 12 | pages = 1125–32 | date = December 2001 | pmid = 11803813 | doi = 10.1016/s0764-4469(01)01392-0 }}
• {{cite journal | vauthors = Hiraoka A, Yano Ki K, Kagami N, Takeshige K, Mio H, Anazawa H, Sugimoto S | title = Stem cell growth factor: in situ hybridization analysis on the gene expression, molecular characterization and in vitro proliferative activity of a recombinant preparation on primitive hematopoietic progenitor cells | journal = The Hematology Journal | volume = 2 | issue = 5 | pages = 307–15 | year = 2002 | pmid = 11920266 | doi = 10.1038/sj.thj.6200118}}
• {{cite journal | vauthors = Ito C, Sato H, Ando K, Watanabe S, Yoshiba F, Kishi K, Furuya A, Shitara K, Sugimoto S, Kohno H, Hiraoka A, Hotta T | title = Serum stem cell growth factor for monitoring hematopoietic recovery following stem cell transplantation | journal = Bone Marrow Transplantation | volume = 32 | issue = 4 | pages = 391–8 | date = August 2003 | pmid = 12900775 | doi = 10.1038/sj.bmt.1704152 | doi-access = free }}
• {{cite journal | vauthors = Lee E, Min HK, Oskeritzian CA, Kambe N, Schwartz LB, Wook Chang H | title = Recombinant human (rh) stem cell factor and rhIL-4 stimulate differentiation and proliferation of CD3+ cells from umbilical cord blood and CD3+ cells enhance FcepsilonR1 expression on fetal liver-derived mast cells in the presence of rhIL-4 | journal = Cellular Immunology | volume = 226 | issue = 1 | pages = 30–6 | date = November 2003 | pmid = 14746805 | doi = 10.1016/j.cellimm.2003.11.001 }}
• {{cite journal | vauthors = Hollenbeck ST, Sakakibara K, Faries PL, Workhu B, Liu B, Kent KC | title = Stem cell factor and c-kit are expressed by and may affect vascular SMCs through an autocrine pathway | journal = The Journal of Surgical Research | volume = 120 | issue = 2 | pages = 288–94 | date = August 2004 | pmid = 15234225 | doi = 10.1016/j.jss.2004.01.005 }}

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• {{UCSC gene info|CLEC11A}}

{{gene-19-stub}}