CLTB

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Clathrin, light chain B is a protein in humans that is encoded by the CLTB gene.{{cite web

| title = Entrez Gene: Clathrin, light chain B

| url = https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=1212

| accessdate = 2013-06-05

}}

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and coated vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].