CLaCS

{{more citations needed|date=May 2014}}

CLaCS (Cryo-Laser and Cryo-Sclerotherapy) is a treatment for leg vein lesions by combining transdermal laser effect and injection sclerotherapy, all under skin cooling (Cryo - cold air blown onto the skin at -20C).{{Cite web |title=Cryo-laser and cryo-sclerotherapy guided by augmented reality for telangiectasias, feeder, and small varicose vein treatment–The CLaCS technique white paper report |url=https://scholar.google.com/citations?view_op=view_citation&hl=pt-BR&user=N96fCRUAAAAJ&citation_for_view=N96fCRUAAAAJ:BrmTIyaxlBUC |access-date=2024-07-10 |website=scholar.google.com}} {{Cite journal |last=Miyake |first=Roberto Kasuo |last2=Chi |first2=Yung-Wei |last3=Franklin |first3=Ian J. |last4=Gianesini |first4=Sergio |date= |title=State of the art on cryo-laser cryo-sclerotherapy in lower limb venous aesthetic treatment |url=https://pubmed.ncbi.nlm.nih.gov/32179040/ |journal=Journal of Vascular Surgery. Venous and Lymphatic Disorders |volume=8 |issue=5 |pages=893–895 |doi=10.1016/j.jvsv.2020.01.003 |issn=2213-3348 |pmid=32179040}}{{Cite journal|last1=Miyake|first1=Hiroshi|last2=Miyake|first2=Kasuo|last3=Duarte|first3=Flávio|last4=Kikuchi|first4=Rodrigo|date=2008|title=Pequenas Varizes e Telangiectasias|trans-title=Small Varicose Veins and Telangiectasias|journal=Doenças Vasculares Periféricas|language=pt|edition=4|location=Rio de Janeiro, RJ|publisher=Guanabara Koogan S.A.|volume=2|pages=1769–1795|isbn=9788527714600}} The laser causes a selective photothermolysis damaging the vein wall. The vein's lumen gets smaller. On a second procedure, sclerosing agent is injected where the vein is still open. This combination can be used treat veins that could be treated by phleboectomy or foam sclerotherapy - more invasive options. To improve results, CLaCS can be guided by Augmented Reality{{Cite news |title=Reality, only better, December 8th |url=https://www.economist.com/letters-to-the-editor-the-inbox/2007/12/19/reality-only-better-december-8th |access-date=2024-07-10 |work=The Economist |issn=0013-0613}}

(near-infrared vein finder).{{cite journal|title= Vein imaging: a new method of near infrared imaging, where a processed image is projected onto the skin for the enhancement of vein treatment|date=2014-01-24 |pmid=16918565 | doi=10.1111/j.1524-4725.2006.32226.x |volume=32 |issue=8 |journal=Dermatol Surg |pages=1031–8 | last1 = Miyake | first1 = RK | last2 = Zeman | first2 = HD | last3 = Duarte | first3 = FH | last4 = Kikuchi | first4 = R | last5 = Ramacciotti | first5 = E | last6 = Lovhoiden | first6 = G | last7 = Vrancken | first7 = C|s2cid=8872471 }}

CLaCS was created by Dr. Roberto Kasuo Miyake (also knowns as Kasuo Miyake), in 1999, to adhere to patients' requests for treatment that did not require hospitalizations.