CNTROB
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Centrobin is a protein that in humans is encoded by the CNTROB gene.{{Cite journal
| pmid = 11984006
| year = 2002
| last1 = Tchernev | first1 = V. T.
| last2 = Mansfield | first2 = T. A.
| last3 = Giot | first3 = L.
| last4 = Kumar | first4 = A. M.
| last5 = Nandabalan | first5 = K.
| last6 = Li | first6 = Y.
| last7 = Mishra | first7 = V. S.
| last8 = Detter | first8 = J. C.
| last9 = Rothberg | first9 = J. M.
| last10 = Wallace | first10 = M. R.
| last11 = Southwick | first11 = F. S.
| last12 = Kingsmore | first12 = S. F.
| title = The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins
| volume = 8
| issue = 1
| pages = 56–64
| pmc = 2039936
| journal = Molecular Medicine | doi=10.1007/bf03402003
}}
It is a centriole-associated protein that asymmetrically localizes to the daughter centriole, and is required for centriole duplication and cytokinesis.{{Cite journal
| doi = 10.1083/jcb.200506185
| pmid = 16275750
| year = 2005
| last1 = Zou | first1 = C.
| last2 = Li | first2 = J.
| last3 = Bai | first3 = Y.
| last4 = Gunning | first4 = W.
| last5 = Wazer | first5 = D.
| last6 = Band | first6 = V.
| last7 = Gao | first7 = Q.
| title = Centrobin: a novel daughter centriole-associated protein that is required for centriole duplication
| volume = 171
| issue = 3
| pages = 437–445
| pmc = 2171251
| journal = Journal of Cell Biology
}}
References
{{reflist}}
External links
- {{UCSC gene info|CNTROB}}
Further reading
{{refbegin | 2}}
- {{cite journal | vauthors=Jeong Y, Lee J, Kim K |title=Characterization of NIP2/centrobin, a novel substrate of Nek2, and its potential role in microtubule stabilization. |journal=J. Cell Sci. |volume=120 |issue= Pt 12 |pages= 2106–16 |year= 2007 |pmid= 17535851 |doi= 10.1242/jcs.03458 |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Lim J, Hao T, Shaw C |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 |s2cid=13709685 |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Wan D, Gong Y, Qin W |title=Large-scale cDNA transfection screening for genes related to cancer development and progression |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 44 |pages= 15724–9 |year= 2004 |pmid= 15498874 |doi= 10.1073/pnas.0404089101 | pmc=524842 |bibcode=2004PNAS..10115724W |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
{{refend}}
{{Centrosome}}
{{gene-17-stub}}