CRB3

This gene encodes a member of the Crumbs family of proteins. This protein may play a role in epithelial cell polarity and is associated with tight junctions at the apical surface of epithelial cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.{{cite web | title = Entrez Gene: CRB3 crumbs homolog 3 (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=92359| accessdate = }}

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• {{UCSC gene info|CRB3}}

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• {{cite journal | vauthors = Lemmers C, Médina E, Delgrossi MH, Michel D, Arsanto JP, Le Bivic A | title = hINADl/PATJ, a homolog of discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cells | journal = The Journal of Biological Chemistry | volume = 277 | issue = 28 | pages = 25408–15 | date = Jul 2002 | pmid = 11964389 | doi = 10.1074/jbc.M202196200 | doi-access = free }}
• {{cite journal | vauthors = Makarova O, Roh MH, Liu CJ, Laurinec S, Margolis B | title = Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1) | journal = Gene | volume = 302 | issue = 1–2 | pages = 21–9 | date = Jan 2003 | pmid = 12527193 | doi = 10.1016/S0378111902010843 }}
• {{cite journal | vauthors = Roh MH, Fan S, Liu CJ, Margolis B | title = The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells | journal = Journal of Cell Science | volume = 116 | issue = Pt 14 | pages = 2895–906 | date = Jul 2003 | pmid = 12771187 | doi = 10.1242/jcs.00500 | doi-access = free }}
• {{cite journal | vauthors = Lemmers C, Michel D, Lane-Guermonprez L, Delgrossi MH, Médina E, Arsanto JP, Le Bivic A | title = CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells | journal = Molecular Biology of the Cell | volume = 15 | issue = 3 | pages = 1324–33 | date = Mar 2004 | pmid = 14718572 | pmc = 363137 | doi = 10.1091/mbc.E03-04-0235 }}
• {{cite journal | vauthors = Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW | title = Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation | journal = Nature Biotechnology | volume = 22 | issue = 6 | pages = 707–16 | date = Jun 2004 | pmid = 15146197 | doi = 10.1038/nbt971 | s2cid = 27764390 }}
• {{cite journal | vauthors = Fogg VC, Liu CJ, Margolis B | title = Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells | journal = Journal of Cell Science | volume = 118 | issue = Pt 13 | pages = 2859–69 | date = Jul 2005 | pmid = 15976445 | doi = 10.1242/jcs.02412 | doi-access = free }}
• {{cite journal | vauthors = Fan S, Fogg V, Wang Q, Chen XW, Liu CJ, Margolis B | title = A novel Crumbs3 isoform regulates cell division and ciliogenesis via importin beta interactions | journal = The Journal of Cell Biology | volume = 178 | issue = 3 | pages = 387–98 | date = Jul 2007 | pmid = 17646395 | pmc = 2064851 | doi = 10.1083/jcb.200609096 }}

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