Calhoun County High School

{{About|the high school in South Carolina|the schools in Georgia and West Virginia with similar names|Calhoun High School (disambiguation){{!}}Calhoun High School}}

{{Use mdy dates|date=January 2025}}

{{Primary sources|date=October 2009}}

{{Infobox school

| name = Calhoun County High School

| image =

| imagesize =

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| caption =

| streetaddress = 150 Saints Avenue

| city = St. Matthews, South Carolina

| zipcode = 29135

| country = United States

| coordinates = {{coord|33|39|55|N|80|47|57|W|type:edu_region:US-SC|display=inline,title}}

| district = Calhoun County Schools

| principal = Milton Howard

| staff =

| teaching_staff = 31.00 (FTE)

| ceeb = 411755

| avg_class_size =

| ratio = 13.48

| schooltype =

| grades = 9–12

| campus size =

| campus type =

| athletics = SCHSL Class AA, Region V

| conference =

| slogan =

| motto =

| mascot = Saint

| colors = Red, black and white
{{color box|#FF0000|border=silver}}{{color box|#000000|border=silver}}{{color box|#ffffff|border=silver}}

| yearbook =

| publication =

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| established =

| enrollment = 418 (2023-2024){{cite web|url=https://nces.ed.gov/ccd/schoolsearch/school_detail.asp?Search=1&DistrictID=4501250&ID=450125000187|title=Calhoun County High|publisher=National Center for Education Statistics|accessdate=March 28, 2025}}

| footnotes =

| picture =

| homepage = {{URL|http://cchs.ccpsonline.net/}}

}}

Calhoun County High School is a public secondary school in St. Matthews, South Carolina, United States.