Caspase 5
{{Short description|Mammalian protein found in humans}}
{{infobox protein
| Name = caspase 5, apoptosis-related cysteine peptidase
| caption =
| image =
| width = 240px
| HGNCid = 1506
| Symbol = CASP5
| AltSymbols = ICE(rel)III, ICH3
| EntrezGene = 838
| OMIM = 602665
| RefSeq = NM_004347
| UniProt = P51878
| PDB =
| ECnumber = 3.4.22.58
| Chromosome = 11
| Arm = q
| Band = 22.2-q22.3
| LocusSupplementaryData =
}}
Caspase 5 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system.{{cite journal |vauthors=Martinon F, Tschopp J |title=Inflammatory caspases and inflammasomes: master switches of inflammation |journal=Cell Death Differ. |volume=14 |issue=1 |pages=10–22 |year=2007 |pmid=16977329 |doi=10.1038/sj.cdd.4402038|doi-access=free }}
See also
References
External links
- The MEROPS online database for peptidases and their inhibitors: [https://archive.today/20121223124946/http://merops.sanger.ac.uk/cgi-bin/merops.cgi?id=C14.008 C14.008]
{{Cysteine proteases}}
{{Enzymes}}
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{{gene-11-stub}}