Caspase 5

{{Short description|Mammalian protein found in humans}}

{{infobox protein

| Name = caspase 5, apoptosis-related cysteine peptidase

| caption =

| image =

| width = 240px

| HGNCid = 1506

| Symbol = CASP5

| AltSymbols = ICE(rel)III, ICH3

| EntrezGene = 838

| OMIM = 602665

| RefSeq = NM_004347

| UniProt = P51878

| PDB =

| ECnumber = 3.4.22.58

| Chromosome = 11

| Arm = q

| Band = 22.2-q22.3

| LocusSupplementaryData =

}}

File:Apop1.png

Caspase 5 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system.{{cite journal |vauthors=Martinon F, Tschopp J |title=Inflammatory caspases and inflammasomes: master switches of inflammation |journal=Cell Death Differ. |volume=14 |issue=1 |pages=10–22 |year=2007 |pmid=16977329 |doi=10.1038/sj.cdd.4402038|doi-access=free }}