Castropignano

{{Infobox Italian comune

| name = Castropignano

| official_name = Comune di Castropignano

| native_name =

| image_skyline = Castello d evoli 2006 illuminato2.JPG

| imagesize =

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| image_caption = Castello d'Evoli by night

| image_shield = Castropignano-Stemma.png

| shield_alt =

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| coordinates = {{coord|41|37|N|14|34|E|type:city(1,107)_region:IT|display=inline,title}}

| coordinates_footnotes =

| region = Molise

| province = Campobasso (CB)

| frazioni = Roccaspromonte

| mayor_party =

| mayor = Nicola Scapillati

| area_footnotes =

| area_total_km2 = 27.0

| population_footnotes = All demographics and other statistics: Italian statistical institute Istat.

| population_total = 923

| population_as_of = 30 June 2017

| pop_density_footnotes =

| population_demonym = Castropignanesi

| elevation_footnotes =

| elevation_m = 590

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| postal_code = 86010

| area_code = 0874

| website = {{official website|http://www.comune.castropignano.cb.it/hh/index.php}}

| footnotes =

}}

Castropignano is a comune (municipality) in the Province of Campobasso in the Italian region Molise, located about {{convert|10|km|mi|0}} northwest of Campobasso.

It is home to a medieval castle, the Castello d'Evoli, built in the mid-fourteenth century, perhaps over the remains of a Samnite fortress.