CatSper4
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
CatSper4, is a protein which in humans is encoded by the CATSPER4 gene.{{cite journal | vauthors = Lobley A, Pierron V, Reynolds L, Allen L, Michalovich D | title = Identification of human and mouse CatSper3 and CatSper4 genes: characterisation of a common interaction domain and evidence for expression in testis | journal = Reprod. Biol. Endocrinol. | volume = 1 | pages = 53 |date=August 2003 | pmid = 12932298 | pmc = 184451 | doi = 10.1186/1477-7827-1-53 | doi-access = free }}{{cite journal | vauthors = Qi H, Moran MM, Navarro B, Chong JA, Krapivinsky G, Krapivinsky L, Kirichok Y, Ramsey IS, Quill TA, Clapham DE | title = All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 104 | issue = 4 | pages = 1219–23 |date=January 2007 | pmid = 17227845 | pmc = 1770895 | doi = 10.1073/pnas.0610286104 | doi-access = free }}{{cite journal | vauthors = Clapham DE, Garbers DL | title = International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels | journal = Pharmacol. Rev. | volume = 57 | issue = 4 | pages = 451–4 |date=December 2005 | pmid = 16382101 | doi = 10.1124/pr.57.4.7 | s2cid = 35096827 }} CatSper1 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells.*{{cite web | url = http://www.iuphar-db.org/IC/FamilyIntroductionForward?familyId=13 | title = CatSper and Two-Pore Channels: Introduction | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | access-date = 2008-12-16 | archive-date = 2012-09-05 | archive-url = https://web.archive.org/web/20120905080216/http://www.iuphar-db.org/IC/FamilyIntroductionForward?familyId=13 | url-status = dead }}