Cetamolol

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| ImageFile = Cetamolol.svg

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| IUPACName = 2-[2-[3-(tert-Butylamino)-2-hydroxypropoxy]phenoxy]-N-methylacetamide

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| CASNo = 34919-98-7

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| CASNo1 = 77590-95-5

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| CASNo1_Comment = (hydrochloride)

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| UNII = Z0VD1633O8

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| UNII1 = 5UNK5C6QM5

| UNII1_Comment = (hydrochloride)

| PubChem = 53698

| ChemSpiderID = 48483

| KEGG = D03449

| ChEMBL = 2105989

| InChI=1S/C16H26N2O4/c1-16(2,3)18-9-12(19)10-21-13-7-5-6-8-14(13)22-11-15(20)17-4/h5-8,12,18-19H,9-11H2,1-4H3,(H,17,20)

| InChIKey= UWCBNAVPISMFJZ-UHFFFAOYSA-N

| SMILES = CC(C)(C)NCC(COC1=CC=CC=C1OCC(=O)NC)O}}

|Section2={{Chembox Properties

| C=16 | H=26 | N=2 | O=4

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Cetamolol is a beta adrenergic antagonist, more specifically a β1-adrenergic blocker.{{cite journal|pmid=2905711|year=1988|last1=Klausner|first1=MA|last2=Irwin|first2=C|last3=Mullane|first3=JF|last4=Shand|first4=DG|last5=Leese|first5=PT|last6=Arnold|first6=JD|last7=Wollberg|first7=W|last8=Wagner|first8=NB|last9=Wagner|first9=GS|title=Effect of cetamolol on epinephrine-induced hypokalemia|volume=28|issue=8|pages=751–6|journal=Journal of Clinical Pharmacology|doi=10.1002/j.1552-4604.1988.tb03210.x|s2cid=30767741 }}

Synthesis

File:Cetamolol synthesis.svg}}{{Cite patent|country=BE|number=767781|pubdate=1971-11-29|title=Alkanolamines|assign1=Imperial Chemical Industries Ltd.}} D. J. Lecount, C. J. Squire, {{US patent|4059622}} (1977 to ICI).]]

References

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{{Adrenergics}}

Category:Beta blockers

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