Cetrimide
{{Short description|Quaternary ammonium surfactant and antiseptic agent}}
{{Chembox
| Name= Cetrimide
| ImageFile = Cetrimide.svg
| ImageAlt =ध
| ImageCaption =
््
|Section1={{Chembox Identifiers
| index_label = Cetrimide
| index1_label = C12
| index2_label = C14
| index3_label = C16
| index_comment = Mixture of
| index1_comment = Dodecyltrimethylammonium bromide
| index2_comment = Tetradecyltrimethylammonium bromide
| index3_comment = Hexadecyltrimethylammonium bromide
| CASNo = 8044-71-1
| CASNo2 = 57-09-0
| CASNo3 = 1119-94-4
| ChemSpiderID1 = 13611
| ChemSpiderID2 = 13612
| ChemSpiderID3 = 5754
| PubChem =
| PubChem1 = 14250
| PubChem2 = 5974
| PubChem3 = 14249
| EC_number= 617-073-5
}}
}}
Cetrimide, or alkyltrimethylammonium bromide, is an antiseptic which is a mixture of three quaternary ammonium compounds: tetradonium bromide (TTAB or MITMAB), cetrimonium bromide (CTAB), and laurtrimonium bromide (DTAB or LTAB).{{cite book | author = Council of Europe | author-link = Council of Europe | title=European Pharmacopoeia (Ph. Eur.) | publisher=The Stationery Office | publication-place=Strasbourg | year=2007 | edition = 6.0 | isbn=978-92-871-6054-6 | oclc=170932841 | pages=1484–5 }} It was first discovered and developed by ICI and introduced under the brand name Cetavlon.{{Cite web |url=http://newspapers.nl.sg/Digitised/Article/straitstimes19721231.2.68.1.aspx |title=Newspaper Article – Page 11 Advertisements Column 1 |access-date=2013-08-15 |archive-url=https://web.archive.org/web/20131005011321/http://newspapers.nl.sg/Digitised/Article/straitstimes19721231.2.68.1.aspx |archive-date=2013-10-05 |url-status=dead }} It is used as a 1-3 % solution for cleaning roadside accident wounds.{{cite book |title=Essentials of Medical Pharmacology |edition=7th |first1=KD |last1=Tripathi |page=900}} ICI also introduced Savlon, which was a combination of cetrimide and chlorhexidine. ICI sold the Savlon brand OTC to Johnson & Johnson in May 1992.{{cite web |url=http://www.thefreelibrary.com/JOHNSON+%26+JOHNSON+ACQUIRES+SAVLON+OTC+BRANDS+FROM+ICI-a012169404 |url-status=dead |archive-url=https://web.archive.org/web/20131005000541/http://www.thefreelibrary.com/JOHNSON+%26+JOHNSON+ACQUIRES+SAVLON+OTC+BRANDS+FROM+ICI-a012169404 |archive-date=2013-10-05 |title=Johnson & Johnson acquires Savlon OTC brands from ICI – Free Online Library}} Cetrimide is used in various applications such as antiseptic agents, diagnostic test and analysis, topical formulations, and dental treatment.{{Cite web|date=22 October 2021|title=Cetrimide Applications|url=https://novonordiskpharmatech.com/products/cetrimide/|url-status=live|archive-url=https://web.archive.org/web/20190405092704/https://novonordiskpharmatech.com/products/cetrimide/ |archive-date=2019-04-05 }}
References
{{Reflist}}
{{Antiseptics and disinfectants}}
{{Other dermatological preparations}}
{{Pharma-stub}}