Cetrimide

{{Short description|Quaternary ammonium surfactant and antiseptic agent}}

{{Chembox

| Name= Cetrimide

| ImageFile = Cetrimide.svg

| ImageAlt =ध

| ImageCaption =

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|Section1={{Chembox Identifiers

| index_label = Cetrimide

| index1_label = C12

| index2_label = C14

| index3_label = C16

| index_comment = Mixture of

| index1_comment = Dodecyltrimethylammonium bromide

| index2_comment = Tetradecyltrimethylammonium bromide

| index3_comment = Hexadecyltrimethylammonium bromide

| CASNo = 8044-71-1

| CASNo2 = 57-09-0

| CASNo3 = 1119-94-4

| ChemSpiderID1 = 13611

| ChemSpiderID2 = 13612

| ChemSpiderID3 = 5754

| PubChem =

| PubChem1 = 14250

| PubChem2 = 5974

| PubChem3 = 14249

| EC_number= 617-073-5

}}

}}

Cetrimide, or alkyltrimethylammonium bromide, is an antiseptic which is a mixture of three quaternary ammonium compounds: tetradonium bromide (TTAB or MITMAB), cetrimonium bromide (CTAB), and laurtrimonium bromide (DTAB or LTAB).{{cite book | author = Council of Europe | author-link = Council of Europe | title=European Pharmacopoeia (Ph. Eur.) | publisher=The Stationery Office | publication-place=Strasbourg | year=2007 | edition = 6.0 | isbn=978-92-871-6054-6 | oclc=170932841 | pages=1484–5 }} It was first discovered and developed by ICI and introduced under the brand name Cetavlon.{{Cite web |url=http://newspapers.nl.sg/Digitised/Article/straitstimes19721231.2.68.1.aspx |title=Newspaper Article – Page 11 Advertisements Column 1 |access-date=2013-08-15 |archive-url=https://web.archive.org/web/20131005011321/http://newspapers.nl.sg/Digitised/Article/straitstimes19721231.2.68.1.aspx |archive-date=2013-10-05 |url-status=dead }} It is used as a 1-3 % solution for cleaning roadside accident wounds.{{cite book |title=Essentials of Medical Pharmacology |edition=7th |first1=KD |last1=Tripathi |page=900}} ICI also introduced Savlon, which was a combination of cetrimide and chlorhexidine. ICI sold the Savlon brand OTC to Johnson & Johnson in May 1992.{{cite web |url=http://www.thefreelibrary.com/JOHNSON+%26+JOHNSON+ACQUIRES+SAVLON+OTC+BRANDS+FROM+ICI-a012169404 |url-status=dead |archive-url=https://web.archive.org/web/20131005000541/http://www.thefreelibrary.com/JOHNSON+%26+JOHNSON+ACQUIRES+SAVLON+OTC+BRANDS+FROM+ICI-a012169404 |archive-date=2013-10-05 |title=Johnson & Johnson acquires Savlon OTC brands from ICI – Free Online Library}} Cetrimide is used in various applications such as antiseptic agents, diagnostic test and analysis, topical formulations, and dental treatment.{{Cite web|date=22 October 2021|title=Cetrimide Applications|url=https://novonordiskpharmatech.com/products/cetrimide/|url-status=live|archive-url=https://web.archive.org/web/20190405092704/https://novonordiskpharmatech.com/products/cetrimide/ |archive-date=2019-04-05 }}

References

{{Reflist}}

{{Antiseptics and disinfectants}}

{{Other dermatological preparations}}

Category:Antiseptics

Category:Cationic surfactants

{{Pharma-stub}}