Charles Claude Guthrie
{{Short description|American physiologist}}
{{Use mdy dates|date=June 2025}}
{{Infobox scientist
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| birth_name =
| birth_date = {{birth date|1880|9|26}}
| birth_place = Gilmore, Missouri
| death_date = {{death date and age |1963|6|17|1880|9|26}}
| death_place = Columbia, Missouri
| fields = Physiology
| workplaces = Washington University, University of Pittsburgh
| education = University of Missouri (M.D. 1901), University of Chicago (Ph.D. 1908}
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| academic_advisors = Alexis Carrel
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| known_for = Blood reactions, head transplants
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Charles Claude Guthrie (September 26, 1880 – June 16, 1963) was an American physiologist.
Early life and education
He was born at Gilmore, Missouri. He graduated (M.D.) from the University of Missouri in 1901 and (Ph.D.) from the University of Chicago in 1908.
Career
Guthrie taught physiology while engaged in advanced studies, and was professor of physiology and pharmacology at Washington University in 1906–1909 and at the University of Pittsburgh after 1909. He was author of Blood-Vessel Surgery and its Applications (1912) and of contributions on blood reactions and alterations, resuscitation, cerebral and other anæmias, isolated and ungrafted tissues, and sutures and anastomosis of blood vessels.
Guthrie collaborated in his work on vascular surgery with French physician Alexis Carrel, who won the 1912 Nobel Prize in Physiology or Medicine. Arguments were made that the primary credit for this work should have gone to Guthrie rather than Carrel.{{cite journal |vauthors=Friedman SG |title=Credit where due |journal=J Vasc Surg |volume=64 |issue=2 |pages=530–533 |date=August 2016 |pmid=27288106 |doi=10.1016/j.jvs.2016.04.033 |url=|doi-access=free }}{{cite journal |title=America's First Nobel Prize in Medicine or Physiology: The Story of Guthrie and Carrel |vauthors=Stephenson HE, Kimpton RS |journal=Texas Heart Institute Journal |year=2002 |volume=29 |issue=2 |pages=150–152 |pmc=116749 }} However, Guthrie's head transplant experiments likely prevented his Nobel Prize candidacy status.{{cn|date=January 2021}}
Death
Guthrie died in Columbia, Missouri, on June 16, 1963.{{cite web|url = https://www.nytimes.com/1963/06/17/archives/charles-guthrie-physiologist-83-bloodvessel-surgeon-dies.html|publisher = NewYork Times|title = CHARLES GUTHRIE, PHYSIOLOGIST, 83; Blood-Vessel Surgeon Dies --Transplanted Dog's Head|access-date=3 June 2025
}}
References
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Category:American physiologists
Category:University of Chicago alumni
Category:University of Missouri alumni
Category:People from St. Charles County, Missouri
Category:Washington University in St. Louis faculty
Category:University of Pittsburgh faculty
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