Childhood asthma

{{Short description|Childhood Asthma}}

Childhood asthma is a chronic respiratory condition characterized by inflammation and narrowing of the airways, leading to recurrent episodes of wheezing, shortness of breath, chest tightness and coughing. Around 4.9 million children in the US suffer from asthma.{{cite web |url=https://aafa.org/asthma/living-with-asthma/asthma-in-children/#:~:text=Around%204.9%20million%20children%20in%20the%20United%20States%20have%20asthma.&text=Asthma%20is%20one%20of%20the,causes%20for%20missed%20school%20days. |title=Asthma in Children |website=Asthma and Allergy Foundation of America}} It is difficult to diagnose asthma in children younger than 6 years of age. There can be multiple factors that can contribute to asthma in childhood such as genetics, allergens, and viral infections.{{cite web |title=Asthma Causes & Risk Factors |url=https://www.lung.org/lung-health-diseases/lung-disease-lookup/asthma/learn-about-asthma/what-causes-asthma#:~:text=The%20most%20common%20factors%20for,industrial%20dusts%20in%20the%20workplace. |website=American Lung Association}} Children are particularly vulnerable to environmental factors that contribute to asthma due to their developing respiratory systems, higher respiratory rates, and increased exposure to outdoor air pollutants during play and school activities. Childhood asthma has been linked to various environmental exposures such as air pollution, allergens, and indoor toxins. Additionally, social determinants such as housing quality, access to healthcare, and socioeconomic status can influence prevalence and outcomes.{{cite journal |last1=Grant |first1=Torie |title=Asthma and the Social Determinants of Health |journal=Ann Allergy Astham Immunol |date=2022 |volume=128 |issue=1 |pages=5–11 |doi=10.1016/j.anai.2021.10.002|pmid=34673220 |pmc=8671352 }}{{Cite journal |last=Holden |first=Karl A. |last2=Hawcutt |first2=Daniel B. |last3=Sinha |first3=Ian P. |date=2025-03-08 |title=Socioeconomic determinants of outcomes in childhood asthma |url=https://linkinghub.elsevier.com/retrieve/pii/S1526054225000284 |journal=Paediatric Respiratory Reviews |doi=10.1016/j.prrv.2025.03.001 |issn=1526-0542}}

Asthma attacks are triggered by infections, dust, psychological and physical stress, or excessive exercise.{{cite journal |last1=Wypych-Ślusarska |first1=A |title=Respiratory Symptoms, Allergies, and Environmental Exposures in Children with and without Asthma |journal=International Journal of Environmental Research and Public Health |date=2022 |volume=19 |issue=18 |page=11180 |doi=10.3390/ijerph191811180 |doi-access=free |pmid=36141448 |pmc=9517590 }} These exacerbations may require medical intervention or hospitalization. Early diagnosis, preventative measures and effective asthma management strategies can significantly improve a child’s well-being and reduce the frequency of attacks. Ongoing public health efforts focus on reducing childhood asthma prevalence through education, improved air quality regulations, environmental control strategies, and expanded access to healthcare.{{cite journal |last1=Mirabelli |first1=Maria |title=CDC's National Asthma Control Program: Public Health Actions to Reduce the Burden of Asthma |journal=Preventing Chronic Disease|date=2024 |volume=21 |pages=E73 |doi=10.5888/pcd21.240344 |pmid=39298794 |pmc=11451571 |url=https://www.cdc.gov/pcd/issues/2024/24_0344.htm}}

Indoor allergens as a risk factor

Asthma exacerbations in children have been associated with exposure to residential indoor environmental stressors such as allergens and air pollutants.{{cite journal |last1=Fabian |first1=M |title=The effects of indoor environmental exposures on pediatric asthma: a discrete event simulation model |journal=Environmental Health |date=2012 |volume=11 |issue=66 |page=66 |doi=10.1186/1476-069X-11-66 |doi-access=free |pmid=22989068 |pmc=3527278 |bibcode=2012EnvHe..11...66F }} Common indoor allergens that contribute to asthma symptoms include dust mites, mold, cockroach droppings, pet dander, and rodent allergens. Dust mites found in bedding, carpets, and upholstery are the most common indoor asthma trigger. Proteins found in cockroach saliva, feces and body parts are also a potent asthma trigger. Studies indicate that sensitization and exposure to cockroach have been associated with increased hospitalizations and asthma related emergencies.{{cite journal |last1=Maciag |first1=M |title=Update on indoor allergens and their impact on pediatric asthma |journal=Ann Allergy Asthma Immunol |date=2021 |volume=128 |issue=6 |pages=652–658 |doi=10.1016/j.anai.2022.02.009 |pmid=35227902 |pmc=9149060 }}

Additionally, tobacco smoke and secondhand exposure increases the likelihood of childhood asthma development and can worsen symptoms. Secondhand smoke contains chemicals including benzene, formaldehyde and carbon monoxide which trigger airway inflammation in children with asthma. Secondhand smoke has been found to be linked to increase in school absence, emergency care, and hospitalization among children with asthma{{cite journal |last1=borrelli |first1=b |title=Children with asthma versus healthy children: differences in second smoke exposure and caregiver perceived risk |journal=Nicotine & Tobacco Research |date=2014 |volume=16 |issue=5 |pages=554–561 |doi=10.1093/ntr/ntt180 |pmid=24306137 |pmc=3977483 |url=https://doi.org/10.1093/ntr/ntt180}}

Prevention

Preventing childhood asthma exacerbations requires a multifaceted approach that includes reducing exposure to environmental triggers, implementing public health policies, and ensuring proper asthma management. One effective strategy is minimizing exposure to common indoor allergens by maintaining clean and well-ventilated living environments.{{cite web |title=How Can I Control Indoor Allergens and Improve Indoor Air Quality? |url=https://aafa.org/allergies/prevent-allergies/control-indoor-allergens/#:~:text=Keep%20surfaces%20in%20your%20home,throw%20rugs%20you%20can%20wash. |website=Asthma and Allergy Foundation of America}}Regular cleaning and washing of bedding to minimize dust mite exposure, as well as, using HEPA filters in vacuum cleaners and air purifiers. Additionally, eliminating exposure to tobacco smoke and secondhand smoke is critical, as studies have shown that decreased exposure has led to decreased asthma related hospitalizations and improved lung function. Additional steps to take in lowering children's risk are keeping homes free of mold and dampness. Mold is a known risk of childhood asthma as stated above in the article.{{cite journal |last1=Xiao |first1=Siyuan |title=Household mold, pesticide use, and childhood asthma: A nationwide study in the U.S. |journal=Int J Hyg Environ Health |date=2021 |volume=233 |issue=113694 |doi=10.1016/j.ijheh.2021.113694 |pmid=33556714|pmc=7965337 |bibcode=2021IJHEH.23313694X }}

Uncontrolled asthma can interfere with daily activities and limit physical activity. Some warning signs are frequent nighttime coughing with waking up a few times a month, coughing during exercise, increased usage of inhaler, or prolonged coughing.{{cite web |last1=Verbanas |first1=Patti |title=Preventing Pediatric Asthma Deaths |url=https://www.rutgers.edu/news/preventing-pediatric-asthma-deaths}}

References