Chris Ponting

{{Infobox scientist

| name = Chris Ponting

| birth_name = Christopher Paul Ponting

| image = Chris Ponting.jpg

| image_size =

| caption =

| birth_date =

| birth_place =

| death_date =

| death_place =

| nationality = British

| fields = {{Plainlist|

| work_institution = University of Edinburgh

| alma_mater = {{Plainlist|

University of Oxford (BA, DPhil)
University of British Columbia (MSc)}}

| doctoral_advisor =

| thesis_title = Structural Studies of Plasminogen and Related Proteins

| thesis_url = http://solo.bodleian.ox.ac.uk/primo_library/libweb/action/display.do?doc=oxfaleph015982470

| thesis_year = 1992

| doctoral_students =

| known_for = SMART{{Cite journal

| last1 = Schultz | first1 = J.

| last2 = Milpetz | first2 = F.

| last3 = Bork | first3 = P.

| author-link3 = Peer Bork

| last4 = Ponting | first4 = C.

| author-link4= Chris Ponting

| title = SMART, a simple modular architecture research tool: Identification of signaling domains

| journal = Proceedings of the National Academy of Sciences of the United States of America

| volume = 95

| issue = 11

| pages = 5857–5864

| year = 1998

| pmid = 9600884

| pmc = 34487

|bibcode = 1998PNAS...95.5857S |doi = 10.1073/pnas.95.11.5857 | doi-access = free

}}

| prizes =

| footnotes =

| website = {{URL|https://www.ed.ac.uk/mrc-human-genetics-unit/research/ponting-group}}

}}

Christopher Paul Ponting is a British computational biologist, specializing in the evolution and function of genes and genomes. He is currently Chair of Medical Bioinformatics at the University of Edinburgh and group leader in the MRC Human Genetics Unit. He is also an Associate Faculty member of the Wellcome Trust Sanger Institute, a Fellow of the Academy of Medical Sciences, member of the European Molecular Biology Organisation and Fellow of the Royal Society of Edinburgh.{{Cite news|url=https://www.rse.org.uk/fellow/chris-ponting/|title=Professor Christopher Paul Ponting FMedSci FRSE - The Royal Society of Edinburgh|work=The Royal Society of Edinburgh|access-date=2018-03-14|language=en-GB}} His research focuses on long noncoding RNA function and evolution, on single cell biology and on disease genomics.{{Scopus|id=7004959561}}{{cite journal | doi = 10.1038/nrg3642 | title=Sequencing depth and coverage: key considerations in genomic analyses | journal=Nature Reviews Genetics | date=2014 | volume=15 | issue=2 | pages=121–132 | first=David | last=Sims | pmid=24434847| s2cid=13325739 }}{{cite journal | doi = 10.1371/journal.pgen.1004525 | title=8.2% of the Human Genome Is Constrained: Variation in Rates of Turnover across Functional Element Classes in the Human Lineage | journal=PLOS Genetics | date=2014 | volume=10 | issue=7 | pages=e1004525 | first=Chris M. | last=Rands | pmid=25057982 | pmc=4109858 | doi-access=free }}{{Cite journal

| pmid = 15057822

| year = 2004

| last1 = Gibbs

| first1 = R. A.

| title = Genome sequence of the Brown Norway rat yields insights into mammalian evolution

| journal = Nature

| volume = 428

| issue = 6982

| pages = 493–521

| last2 = Weinstock

| first2 = G. M.

| last3 = Metzker

| first3 = M. L.

| last4 = Muzny

| first4 = D. M.

| last5 = Sodergren

| first5 = E. J.

| last6 = Scherer

| first6 = S

| last7 = Scott

| first7 = G

| last8 = Steffen

| first8 = D

| last9 = Worley

| first9 = K. C.

| last10 = Burch

| first10 = P. E.

| last11 = Okwuonu

| first11 = G

| last12 = Hines

| first12 = S

| last13 = Lewis

| first13 = L

| last14 = Deramo

| first14 = C

| last15 = Delgado

| first15 = O

| last16 = Dugan-Rocha

| first16 = S

| last17 = Miner

| first17 = G

| last18 = Morgan

| first18 = M

| last19 = Hawes

| first19 = A

| last20 = Gill

| first20 = R

| last22 = Holt

| first22 = R. A.

| last23 = Adams

| first23 = M. D.

| last24 = Amanatides

| first24 = P. G.

| last25 = Baden-Tillson

| first25 = H

| last26 = Barnstead

| first26 = M

| last27 = Chin

| first27 = S

| last28 = Evans

| first28 = C. A.

| last29 = Ferriera

| first29 = S

| last30 = Fosler

| first30 = C

| display-authors = 29

| doi = 10.1038/nature02426

| bibcode = 2004Natur.428..493G

| author21 = Celera

| doi-access = free

}}{{Cite journal | pmid = 17994087| year = 2007| last1 = Drosophila 12 Genomes| first1 = Consortium| title = Evolution of genes and genomes on the Drosophila phylogeny| journal = Nature| volume = 450| issue = 7167| pages = 203–18| last2 = Clark| first2 = A. G.| last3 = Eisen| first3 = M. B.| author-link3 = Michael Eisen| last4 = Smith| first4 = D. R.| last5 = Bergman| first5 = C. M.| last6 = Oliver| first6 = B| last7 = Markow| first7 = T. A.| last8 = Kaufman| first8 = T. C.| last9 = Kellis| first9 = M| last10 = Gelbart| first10 = W| last11 = Iyer| first11 = V. N.| last12 = Pollard| first12 = D. A.| last13 = Sackton| first13 = T. B.| last14 = Larracuente| first14 = A. M.| last15 = Singh| first15 = N. D.| last16 = Abad| first16 = J. P.| last17 = Abt| first17 = D. N.| last18 = Adryan| first18 = B| last19 = Aguade| first19 = M| last20 = Akashi| first20 = H| last21 = Anderson| first21 = W. W.| last22 = Aquadro| first22 = C. F.| last23 = Ardell| first23 = D. H.| last24 = Arguello| first24 = R| last25 = Artieri| first25 = C. G.| last26 = Barbash| first26 = D. A.| last27 = Barker| first27 = D| last28 = Barsanti| first28 = P| last29 = Batterham| first29 = P| last30 = Batzoglou| first30 = S| display-authors = 29| doi = 10.1038/nature06341|bibcode = 2007Natur.450..203C | doi-access = free}}{{Cite journal

| pmid = 12520011

| pmc = 165493

| year = 2003

| last1 = Mulder

| first1 = N. J.

| title = The InterPro Database, 2003 brings increased coverage and new features

| journal = Nucleic Acids Research

| volume = 31

| issue = 1

| pages = 315–8

| last2 = Apweiler

| first2 = R

| author-link2 = Rolf Apweiler

| last3 = Attwood

| first3 = T. K.

| author-link3 = Terri Attwood

| last4 = Bairoch

| first4 = A

| author-link4 = Amos Bairoch

| last5 = Barrell

| first5 = D

| last6 = Bateman

| first6 = A

| author-link6 = Alex Bateman

| last7 = Binns

| first7 = D

| last8 = Biswas

| first8 = M

| last9 = Bradley

| first9 = P

| last10 = Bork

| first10 = P

| author-link10 = Peer Bork

| last11 = Bucher

| first11 = P

| last12 = Copley

| first12 = R. R.

| last13 = Courcelle

| first13 = E

| last14 = Das

| first14 = U

| last15 = Durbin

| first15 = R

| author-link15 = Richard M. Durbin

| last16 = Falquet

| first16 = L

| last17 = Fleischmann

| first17 = W

| last18 = Griffiths-Jones

| first18 = S

| last19 = Haft

| first19 = D

| last20 = Harte

| first20 = N

| last21 = Hulo

| first21 = N

| last22 = Kahn

| first22 = D

| last23 = Kanapin

| first23 = A

| last24 = Krestyaninova

| first24 = M

| last25 = Lopez

| first25 = R

| last26 = Letunic

| first26 = I

| last27 = Lonsdale

| first27 = D

| last28 = Silventoinen

| first28 = V.

| last29 = Orchard

| first29 = S. E.

| last30 = Pagni

| first30 = M.

| last31 = Pagni

| first31 = Marco

| last32 = Peyruc

| first32 = D.

| last33 = Ponting

| first33 = C.P.

| author-link33 =Chris Ponting

| last34 = Selengut

| first34 = J.D.

| last35 = Servant

| first35 = F.

| last36 = Sigrist

| first36 = C.J.A.

| last37 = Vaughan

| first37 = R.

| last38 = Zdobnov

| first38 = E.M.

| doi=10.1093/nar/gkg046

}} Outside of science, Chris is an amateur novelist and wrote an unpublished, science fiction novel about engineered viruses.[https://www.bioinformaticscro.com/podcast/chris-ponting/ The Bioinformatics CRO Podcast]. Episode 2, 2020.

Education

After receiving his Bachelor of Arts and Master of Science in physics from University of Oxford and the University of British Columbia, respectively, he returned to Oxford, completing his Doctor of Philosophy in biophysics in 1992 on structural studies of plasminogen.{{cite thesis |degree=DPhil |first=Christopher Paul|last=Ponting |title=Structural Studies of Plasminogen and Related Proteins |publisher=University of Oxford |date=1992 |url=http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386861|oclc=556763136}}{{cite web |url=http://www.mrcfgu.ox.ac.uk/research/chris-p-ponting|archive-url=https://web.archive.org/web/20140407182834/http://www.mrcfgu.ox.ac.uk/research/chris-p-ponting |title= Prof. Chris P Ponting BA MSc DPhil |archive-date=2014-04-07 |publisher=University of Oxford}}

Research

Ponting contributed to the Human Genome Project,{{Cite journal | first1 = E. S.

| last1 = Lander

| author-link1 = Eric Lander

| last2 = Linton | first2 = M.

| last3 = Birren | first3 = B.

| last4 = Nusbaum | first4 = C.

| last5 = Zody | first5 = C.

| last6 = Baldwin | first6 = J.

| last7 = Devon | first7 = K.

| last8 = Dewar | first8 = K.

| title = Initial sequencing and analysis of the human genome

| journal = Nature

| volume = 409

| issue = 6822

| pages = 860–921

| date =Feb 2001

| issn = 0028-0836

| pmid = 11237011

| doi = 10.1038/35057062|bibcode = 2001Natur.409..860L | doi-access = free | hdl = 2027.42/62798 | hdl-access = free }} and participated in sequence comparison for the mouse,{{Cite journal | last1 = Chinwalla | first1 = A. T. | last2 = Waterston | first2 = L. L. | last3 = Lindblad-Toh | first3 = K. D. | last4 = Birney | first4 = G. A. | last5 = Rogers | first5 = L. A. | last6 = Abril | first6 = R. S. | last7 = Agarwal | first7 = T. A. | last8 = Agarwala | first8 = L. W. | last9 = Ainscough | first9 = E. R. | last10 = Alexandersson | doi = 10.1038/nature01262 | first10 = J. D. | last11 = An | first11 = T. L. | last12 = Antonarakis | first12 = W. E. | last13 = Attwood | first13 = J. O. | last14 = Baertsch | first14 = M. N. | last15 = Bailey | first15 = K. H. | last16 = Barlow | first16 = C. S. | last17 = Beck | first17 = T. C. | last18 = Berry | first18 = B. | last19 = Birren | first19 = J. | last20 = Bloom | first20 = E. | last21 = Bork | first21 = R. H. | last22 = Botcherby | first22 = M. C. | last23 = Bray | first23 = R. K. | last24 = Brent | first24 = S. P. | last25 = Brown | first25 = P. | last26 = Brown | first26 = E. | last27 = Bult | first27 = B. | last28 = Burton | first28 = T. | last29 = Butler | first29 = D. G. | last30 = Campbell | first30 = J. | title = Initial sequencing and comparative analysis of the mouse genome | journal = Nature | volume = 420 | issue = 6915 | pages = 520–562 | year = 2002 | pmid = 12466850 |bibcode = 2002Natur.420..520W | display-authors = 29 | doi-access = free }} rat,{{cite news |first=Jonathan |last=Amos |url=http://news.bbc.co.uk/1/hi/sci/tech/3586573.stm |title=Rat's 'life code' read by science |work=BBC News |date=31 March 2004 |access-date=19 December 2008}} chicken,{{cite news |url=http://news.bbc.co.uk/1/hi/sci/tech/4079283.stm |title=Chicken gives up genetic secrets |work=BBC News |date=9 December 2004 |access-date=19 December 2008}} dog,{{Cite journal | last1 = Lindblad-Toh | first1 = K. | last2 = Wade | first2 = C. M. | last3 = Mikkelsen | first3 = T. S. | last4 = Karlsson | first4 = E. K. | last5 = Jaffe | first5 = D. B. | last6 = Kamal | first6 = M. | last7 = Clamp | first7 = M. | last8 = Chang | first8 = J. L. | last9 = Kulbokas | first9 = E. J. | last10 = Zody | doi = 10.1038/nature04338 | first10 = M. C. | last11 = Mauceli | first11 = E. | last12 = Xie | first12 = X. | last13 = Breen | first13 = M. | last14 = Wayne | first14 = R. K. | last15 = Ostrander | first15 = E. A. | last16 = Ponting | first16 = C. P. | last17 = Galibert | first17 = F. | last18 = Smith | first18 = D. R. | last19 = Dejong | first19 = P. J. | last20 = Kirkness | first20 = E. | last21 = Alvarez | first21 = P. | last22 = Biagi | first22 = T. | last23 = Brockman | first23 = W. | last24 = Butler | first24 = J. | last25 = Chin | first25 = C. W. | last26 = Cook | first26 = A. | last27 = Cuff | first27 = J. | last28 = Daly | first28 = M. J. | last29 = Decaprio | first29 = D. | last30 = Gnerre | first30 = S. | title = Genome sequence, comparative analysis and haplotype structure of the domestic dog | journal = Nature | volume = 438 | issue = 7069 | pages = 803–819 | year = 2005 | pmid = 16341006| bibcode = 2005Natur.438..803L | display-authors = 29 | doi-access = free }} opossum,{{Cite journal

| last1 = Mikkelsen | first1 = T. S.

| last2 = Wakefield | first2 = M. J.

| last3 = Aken | first3 = B.

| last4 = Amemiya | first4 = C. T.

| last5 = Chang | first5 = J. L.

| last6 = Duke | first6 = S.

| last7 = Garber | first7 = M.

| last8 = Gentles | first8 = A. J.

| last9 = Goodstadt | first9 = L.

| last10 = Heger

| doi = 10.1038/nature05805 | first10 = A.

| last11 = Jurka | first11 = J.

| last12 = Kamal | first12 = M.

| last13 = Mauceli | first13 = E.

| last14 = Searle | first14 = S. M. J.

| last15 = Sharpe | first15 = T.

| last16 = Baker | first16 = M. L.

| last17 = Batzer | first17 = M. A.

| last18 = Benos | first18 = P. V.

| last19 = Belov | first19 = K.

| last20 = Clamp | first20 = M.

| last21 = Cook | first21 = A.

| last22 = Cuff | first22 = J.

| last23 = Das | first23 = R.

| last24 = Davidow | first24 = L.

| last25 = Deakin | first25 = J. E.

| last26 = Fazzari | first26 = M. J.

| last27 = Glass | first27 = J. L.

| last28 = Grabherr | first28 = M.

| last29 = Greally | first29 = J. M.

| last30 = Gu | first30 = W.

| title = Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

| journal = Nature

| volume = 447

| issue = 7141

| pages = 167–177

| year = 2007

| pmid = 17495919

|bibcode = 2007Natur.447..167M | display-authors = 29

| doi-access = free

| hdl = 1885/57171

| hdl-access = free

}} and platypus{{Cite journal | last1 = Warren | first1 = W. C. | last2 = Hillier | first2 = L. W. | last3 = Marshall Graves | first3 = J. A. | last4 = Birney | first4 = E. | author-link4 = Ewan Birney| last5 = Ponting | first5 = C. P. | author-link5 = Chris Ponting| last6 = Grützner | first6 = F. | last7 = Belov | first7 = K. | last8 = Miller | first8 = W. | last9 = Clarke | first9 = L. | last10 = Chinwalla | doi = 10.1038/nature06936 | first10 = A. T. | last11 = Yang | first11 = S. P. | last12 = Heger | first12 = A. | last13 = Locke | first13 = D. P. | last14 = Miethke | first14 = P. | last15 = Waters | first15 = P. D. | last16 = Veyrunes | first16 = F. D. R. | last17 = Fulton | first17 = L. | last18 = Fulton | first18 = B. | last19 = Graves | first19 = T. | last20 = Wallis | first20 = J. | last21 = Puente | first21 = X. S. | last22 = López-Otín | first22 = C. | last23 = Ordóñez | first23 = G. R. | last24 = Eichler | first24 = E. E. | last25 = Chen | first25 = L. | last26 = Cheng | first26 = Z. | last27 = Deakin | first27 = J. E. | last28 = Alsop | first28 = A. | last29 = Thompson | first29 = K. | last30 = Kirby | first30 = P. | title = Genome analysis of the platypus reveals unique signatures of evolution | journal = Nature | volume = 453 | issue = 7192 | pages = 175–183 | year = 2008 | pmid = 18464734| pmc =2803040 |bibcode = 2008Natur.453..175W | display-authors = 29 }}http://www.nature.com/nature/videoarchive/platypusgenome/ Discussing the platypus genome{{cite news |first=Helen |last=Briggs |url=http://news.bbc.co.uk/1/hi/sci/tech/7385949.stm |title=Platypus genetic code unravelled |work=BBC News |date=7 May 2008 |access-date=19 December 2008}} Genome Projects. He has also used comparative genomics to contribute directly to the understanding of chromatin structure{{Cite journal | last1 = Jenuwein | first1 = T. | last2 = Eisenhaber | first2 = S. | last3 = O'Carroll | first3 = F. | last4 = Strahl | first4 = D. N. | last5 = Sun | first5 = B. D. | last6 = Schmid | first6 = Z. W. | last7 = Opravil | first7 = M. | last8 = Mechtler | first8 = S. | last9 = Ponting | first9 = K. | last10 = Allis | first10 = C. P. | last11 = Jenuwein | first11 = C. D. | title = Regulation of chromatin structure by site-specific histone H3 methyltransferases | journal = Nature | volume = 406 | issue = 6796 | pages = 593–599 | doi = 10.1038/35020506 | year = 2000 | pmid = 10949293| bibcode = 2000Natur.406..593R | s2cid = 205008015 }} and the genetics of numerous conditions including asthma,{{Cite journal | last1 = Zhang | first1 = Y. | last2 = Leaves | first2 = N. I. | last3 = Anderson | first3 = G. G. | last4 = Ponting | first4 = C. P. | author-link4 = Chris Ponting| last5 = Broxholme | first5 = J. | last6 = Holt | first6 = R. | last7 = Edser | first7 = P. | last8 = Bhattacharyya | first8 = S. | last9 = Dunham | first9 = A. | last10 = Adcock | doi = 10.1038/ng1166 | first10 = I. M. | last11 = Pulleyn | first11 = L. | last12 = Barnes | first12 = P. J. | last13 = Harper | first13 = J. I. | last14 = Abecasis | first14 = G. A. | last15 = Cardon | first15 = L. | last16 = White | first16 = M. | last17 = Burton | first17 = J. | last18 = Matthews | first18 = L. | last19 = Mott | first19 = R. | last20 = Ross | first20 = M. | last21 = Cox | first21 = R. | last22 = Moffatt | first22 = M. F. | last23 = Cookson | first23 = W. O. C. M. | title = Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma | journal = Nature Genetics | volume = 34 | issue = 2 | pages = 181–186 | year = 2003 | pmid = 12754510| hdl = 10044/1/57392 | s2cid = 20807679 | hdl-access = free }} obesity,{{Cite journal | last1 = Gerken | first1 = T. | last2 = Girard | first2 = C. A. | last3 = Tung | first3 = Y. -C. L. | last4 = Webby | first4 = C. J. | last5 = Saudek | first5 = V. | last6 = Hewitson | first6 = K. S. | last7 = Yeo | first7 = G. S. H. | last8 = McDonough | first8 = M. A. | last9 = Cunliffe | first9 = S. | last10 = McNeill | doi = 10.1126/science.1151710 | first10 = L. A. | last11 = Galvanovskis | first11 = J. | last12 = Rorsman | first12 = P. | author-link12 = Patrik Rorsman| last13 = Robins | first13 = P. | last14 = Prieur | first14 = X. | last15 = Coll | first15 = A. P. | last16 = Ma | first16 = M. | last17 = Jovanovic | first17 = Z. | last18 = Farooqi | first18 = I. S. | last19 = Sedgwick | first19 = B. | last20 = Barroso | first20 = I. | last21 = Lindahl | first21 = T. | author-link21 = Tomas Lindahl| last22 = Ponting | first22 = C. P. | author-link22 = Chris Ponting| last23 = Ashcroft | first23 = F. M. | author-link23 = Frances Ashcroft| last24 = O'Rahilly | first24 = S. | author-link24 = Stephen O'Rahilly| last25 = Schofield | first25 = C. J. | author-link25 = Christopher J. Schofield | title = The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase | journal = Science | volume = 318 | issue = 5855 | pages = 1469–1472 | year = 2007 | pmid = 17991826| pmc =2668859 |bibcode = 2007Sci...318.1469G }} Alzheimer's disease,{{Cite journal | last1 = Ponting | first1 = C. P. | author-link1 = Chris Ponting| last2 = Hutton | first2 = M. | last3 = Nyborg | first3 = A. | last4 = Baker | first4 = M. | last5 = Jansen | first5 = K. | last6 = Golde | first6 = T. E. | title = Identification of a novel family of presenilin homologues | doi = 10.1093/hmg/11.9.1037 | journal = Human Molecular Genetics | volume = 11 | issue = 9 | pages = 1037–1044 | year = 2002 | pmid = 11978763| doi-access = free }} retinitis pigmentosa,{{Cite journal | last1 = Abd El-Aziz | first1 = M. M. | last2 = Barragan | first2 = I. | last3 = O'Driscoll | first3 = C. A. | last4 = Goodstadt | first4 = L. | last5 = Prigmore | first5 = E. | last6 = Borrego | first6 = S. | last7 = Mena | first7 = M. | last8 = Pieras | first8 = J. I. | last9 = El-Ashry | first9 = M. F. | last10 = Safieh | doi = 10.1038/ng.241 | first10 = L. A. | last11 = Shah | first11 = A. | last12 = Cheetham | first12 = M. E. | last13 = Carter | first13 = N. P. | last14 = Chakarova | first14 = C. | last15 = Ponting | first15 = C. P. | last16 = Bhattacharya | first16 = S. S. | last17 = Antinolo | first17 = G. | title = EYS, encoding an ortholog of Drosophila spacemaker, is mutated in autosomal recessive retinitis pigmentosa | journal = Nature Genetics | volume = 40 | issue = 11 | pages = 1285–1287 | year = 2008 | pmid = 18836446| pmc =2719291 }} muscular dystrophies,{{Cite journal | last1 = Dickens | first1 = N. J. | last2 = Beatson | first2 = S. | last3 = Ponting | first3 = C. P. | author-link3 = Chris Ponting| doi = 10.1016/S0960-9822(02)00748-0 | title = Cadherin-like domains in α-dystroglycan, α/ε-sarcoglycan and yeast and bacterial proteins | journal = Current Biology | volume = 12 | issue = 6 | pages = R197–R199 | year = 2002 | pmid = 11909544| s2cid = 15872294 | doi-access = free | bibcode = 2002CBio...12.R197D }} and Aicardi–Goutières syndrome.{{Cite journal | last1 = Crow | first1 = Y. J. | last2 = Leitch | first2 = A. | last3 = Hayward | first3 = B. E. | last4 = Garner | first4 = A. | last5 = Parmar | first5 = R. | last6 = Griffith | first6 = E. | last7 = Ali | first7 = M. | last8 = Semple | first8 = C. | last9 = Aicardi | first9 = J. | last10 = Babul-Hirji | doi = 10.1038/ng1842 | first10 = R. | last11 = Baumann | first11 = C. | last12 = Baxter | first12 = P. | last13 = Bertini | first13 = E. | last14 = Chandler | first14 = K. E. | last15 = Chitayat | first15 = D. | last16 = Cau | first16 = D. | last17 = Déry | first17 = C. | last18 = Fazzi | first18 = E. | last19 = Goizet | first19 = C. | last20 = King | first20 = M. D. | last21 = Klepper | first21 = J. | last22 = Lacombe | first22 = D. | last23 = Lanzi | first23 = G. | last24 = Lyall | first24 = H. | last25 = Martínez-Frías | first25 = M. A. L. | last26 = Mathieu | first26 = M. L. | last27 = McKeown | first27 = C. | last28 = Monier | first28 = A. | last29 = Oade | first29 = Y. | last30 = Quarrell | first30 = O. W. | title = Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection | journal = Nature Genetics | volume = 38 | issue = 8 | pages = 910–916 | year = 2006 | pmid = 16845400 | s2cid = 8076225 }}

Additionally, his lab is part of DecodeME, a genetic study to determine the potential causes of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).[https://www.ed.ac.uk/mrc-human-genetics-unit/research/ponting-group Chris Ponting Research Group] MRC Human Genetics Research Unit. July 2021.

References

Category:British geneticists

Category:Living people

Category:Alumni of the University of Oxford

Category:Academics of the University of Edinburgh

Category:British bioinformaticians

Category:Human Genome Project scientists

Category:Year of birth missing (living people)