Clorprenaline

{{Short description|Bronchodilator}}

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| image = Clorprenaline.svg

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| class = Sympathomimetic; Bronchodilator; Sympathomimetic

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| CAS_number = 3811-25-4

| CAS_supplemental =
5588-22-7 (hydrochloride)

| PubChem = 2810

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| ChemSpiderID = 2708

| UNII = 3W4327W76O

| KEGG = D01835

| ChEBI = 146226

| ChEMBL = 1902627

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| synonyms = Chlorprenaline; Isoprophenamine; Compound 20025; L-20025; 2-Chloro-β-hydroxy-N-isopropylphenethylamine

| IUPAC_name = 1-(2-chlorophenyl)-2-(propan-2-ylamino)ethanol

| C=11 | H=16 | Cl=1 | N=1 | O=1

| SMILES = CC(C)NCC(C1=CC=CC=C1Cl)O

| StdInChI = 1S/C11H16ClNO/c1-8(2)13-7-11(14)9-5-3-4-6-10(9)12/h3-6,8,11,13-14H,7H2,1-2H3

| StdInChIKey = SSMSBSWKLKKXGG-UHFFFAOYSA-N

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Clorprenaline ({{Abbrlink|INN|International Nonproprietary Name}}, {{Abbrlink|USAN|United States Adopted Name}}, {{Abbrlink|BAN|British Approved Name}}), also known as isoprophenamine and known as clorprenaline hydrochloride ({{Abbrlink|USAN|United States Adopted Name}}, {{Abbrlink|JAN|Japanese Accepted Name}}) in the case of the hydrochloride salt, is a sympathomimetic and bronchodilator medication which is marketed in Japan.{{cite book | vauthors = Elks J | title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies | publisher=Springer US | year=2014 | isbn=978-1-4757-2085-3 | url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA305 | access-date=17 October 2024 | page=305}}{{cite book | author=Schweizerischer Apotheker-Verein | title=Index Nominum: International Drug Directory | publisher=Medpharm Scientific Publishers | year=2004 | isbn=978-3-88763-101-7 | url=https://books.google.com/books?id=EgeuA47Ocm4C&pg=PA309 | access-date=17 October 2024 | page=309}}{{cite book | vauthors = Morton IK, Hall JM | title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms | publisher=Springer Netherlands | year=2012 | isbn=978-94-011-4439-1 | url=https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA80 | access-date=17 October 2024 | page=80}} It acts as a β-adrenergic receptor agonist or as a β-sympathomimetic. Brand names of clorprenaline in Japan are numerous and include Asnormal, Bazarl, Bronchon, Clopinerin, Conselt, Cosmoline, Fusca, Kalutein, Pentadoll, Restanolon, and Troberin. The drug was first described in the literature by 1956.{{cite journal | vauthors = Gibson WR, Powell CE, Swanson EE | title = The pharmacological action of 1-o-chlorophenyl-2-isopropylaminoethanol (isoprophenamine); a bronchodilator | journal = J Am Pharm Assoc | volume = 45 | issue = 12 | pages = 785–787 | date = December 1956 | pmid = 13376372 | doi = 10.1002/jps.3030451205| url = }}