Comprehensive Physiology

{{Infobox journal

| title = Comprehensive Physiology

| cover =

| editor = Dr. J. Usha Raj, MD, MHA

| discipline = Physiology

| former_names =

| abbreviation = Compr. Physiol.

| publisher = John Wiley & Sons on behalf of the American Physiological Society

| country = United States

| frequency = Bi-Monthly

| history =

| openaccess = Hybrid

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| website = https://onlinelibrary.wiley.com/journal/20404603

| link1 = https://onlinelibrary.wiley.com/loi/20404603

| link1-name = View All Issues

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| link2-name =

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| ISSN = 2040-4603

| eISSN =

}}

Comprehensive Physiology is a peer-reviewed scientific journal published by John Wiley & Sons on behalf of the American Physiological Society.

The journal was relaunched in 2025 to include research articles, reviews, and editorials. Now, [https://onlinelibrary.wiley.com/journal/20404603?SeriesKey=10.1002/cphy Comprehensive Physiology] publishes articles in the interdisciplinary field of inter-organ communication in health and disease. Example topics include inter-organ cellular communication, signaling pathways, organ crosstalk, systems biology, inter-organ pathology and pathogenesis, and the role of hormones and neurotransmitters. The journal provides essential insights for developing interventions and treatments.{{Cite web |title=Comprehensive Physiology, Wiley Online Library |url=https://onlinelibrary.wiley.com/page/journal/20404603/homepage/productinformation.html |access-date=February 10, 2025 |website=Wiley Online Library}}

Previously, the journal consisted of invited review articles, published in quarterly issues, and includes over 30,000 pages of the APS's Handbook of Physiology series of books, scanned and presented online for the first time.1. Carroll RG, Frank M, Ra'anan A, Matyas ML. [http://advan.physiology.org/content/37/1/1.full APS: 125 years of progress of physiology as a scientific discipline and a profession]. Adv Physiol Educ 37: 1-9, 2013. "In the years approaching its 125th anniversary, APS publication efforts continue to diversify. The quarterly journal Comprehensive Physiology, published as a joint effort with John Wiley & Sons, was established to fill the role previously played by the Handbook of Physiology series..."2. [http://www.the-aps.org/mm/Publications/Journals/Physiologist/2010-present/2013/February.pdf APS council holds fall meeting.] The Physiologist 56:1, 2013, p. 5.

David Pollock, Georgia Health Sciences Univ., was selected as the editor of Comprehensive Physiology; beginning July 1, 2013.

The journal is indexed in PubMed, and Web of Knowledge.{{cite web|url=http://www.comprehensivephysiology.com/WileyCDA/Section/id-410603.html|title=About - Comprehensive Physiology|website=www.comprehensivephysiology.com}}