Conofoline

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| ImageFile = Conofoline.svg

| ImageClass = skin-invert-image

| PIN = Methyl (1aS,1′aS,1bS,1′bS,1b1R,1′b1R,3aS,8bS,8′bR,12′R,12aR,12′aR)-1b,1′b-diethyl-7′-hydroxy-5′,6′-dimethoxy-4-methyl-1a,1′a,1b,1′b,1b1,1′b1,2,2′,3,3a,4,4′,9,9′,10,10′,12a,12′a-octadecahydro-12H,12′H-[7,12′-bioxireno[2′,3′:6,7]indolizino[8,1-cd]carbazole]-3′-carboxylate

|Section1={{Chembox Identifiers

| PubChem = 15215005

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| ChemSpiderID = 30824499

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| ChEMBL = 2409161

| StdInChI=1S/C43H52N4O7/c1-7-40-12-11-28-42(13-15-46(38(40)42)20-27-35(40)53-27)23-17-21(9-10-25(23)45(28)3)30-33-36(54-33)41(8-2)19-22(37(49)52-6)34-43(14-16-47(30)39(41)43)24-18-26(48)31(50-4)32(51-5)29(24)44-34/h9-10,17-18,27-28,30,33,35-36,38-39,44,48H,7-8,11-16,19-20H2,1-6H3/t27-,28+,30-,33-,35-,36-,38+,39+,40-,41-,42+,43+/m1/s1

| StdInChIKey = AXBZVPIBJWOFHO-XMONSFOZSA-N

| SMILES = CC[C@]12CC[C@H]3[C@@]4([C@H]1N(CC4)C[C@@H]5[C@H]2O5)C6=C(N3C)C=CC(=C6)[C@@H]7[C@@H]8[C@@H](O8)[C@]9(CC(=C1[C@@]2([C@H]9N7CC2)C2=CC(=C(C(=C2N1)OC)OC)O)C(=O)OC)CC

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|Section2={{Chembox Properties

| C=43 | H=52 | N=4 | O=7

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Conofoline is an alkaloid of the vinca alkaloid class which is closely related to conophylline. It is found in the leaves of some species in the genus Tabernaemontana,{{cite patent | country = US | number = 20070232533 | url = https://patents.google.com/patent/US20070232533 | title = Use of Vinca Alkaloids and Salts Thereof }} including Tabernaemontana divaricata, and in Ervatamia peduncularis.{{cite book |last1=Buckingham |first1=John |last2=Baggaley |first2=Keith H. |last3=Roberts |first3=Andrew D. |last4=Szabo |first4=Laszlo F. |title=Dictionary of Alkaloids with CD-ROM |date=2010 |publisher=CRC Press |isbn=978-1-4200-7770-4 |page=453 |url=https://books.google.com/books?id=mynNBQAAQBAJ&pg=PA453 |language=en}}

See also

References