Coricidin

{{Short description|Brand name for a cough and pain medicine}}

{{Infobox drug

| drug_name =

| INN =

| type = combo

| image = Dextromethorphan.svg

| image2 = Chlorphenamine.svg

| alt =

| caption = Chemical structures of dextromethorphan (top) and chlorpheniramine

| component1 = Dextromethorphan

| class1 = cough suppressant

| component2 = Chlorpheniramine

| class2 = antihistamine

| pronounce =

| tradename = Coricidin 'D'

| Drugs.com =

| MedlinePlus =

| pregnancy_AU =

| pregnancy_AU_comment =

| pregnancy_US =

| pregnancy_category=

| routes_of_administration =

| legal_AU =

| legal_AU_comment =

| legal_CA =

| legal_DE =

| legal_NZ =

| legal_UK =

| legal_US =

| legal_UN =

| legal_status =

| bioavailability =

| protein_bound =

| metabolism = CYP2D6 isozyme of Cytochrome P450

| metabolites =

| onset =

| elimination_half-life =

| duration_of_action =

| excretion =

| CAS_number_Ref = {{cascite|correct|CAS}}

| CAS_number = 125-71-3

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 7355X3ROTS

| class =

| ATCvet =

| ATC_prefix =

| ATC_suffix =

| PubChem =

| DrugBank =

| chemical_formula =

| molecular_weight =

}}

Coricidin, Coricidin 'D' (decongestant), or Coricidin HBP (for high blood pressure), is the name of an over-the-counter cough and cold combination drug containing dextromethorphan (a cough suppressant) and chlorpheniramine maleate (a first-generation antihistamine).{{cite web |title=Label: Coricidin HBP Cold and Flu |url=https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=763a5334-a741-4678-9947-603776622450 |publisher=DailyMed |date=December 30, 2021}} Introduced by Schering-Plough in 1949 as one of the first antihistamines, it is now owned by Bayer.{{cite web |title=Coricidin Meaning |url=https://www.dictionary.com/e/pop-culture/coricidin/ |publisher=Dictionary.com |date=March 12, 2018}}{{cite web |title=Schering-Plough profile |url=https://www.adbrands.net/archive/us/scheringplough_us_p.htm |publisher=adbrands.net |date=June 24, 2016}} Varieties of Coricidin may also contain acetaminophen (an analgesic/antipyretic) and guaifenesin (an expectorant).

Medicinal use

Coricidin is used to alleviate common cold symptoms such as coughs and congestion. Other versions of Coricidin are used to reduce fever or as an expectorant, while Coricidin HBP includes chlorpheniramine for people with high blood pressure. Side effects can include diarrhea and hallucination.[http://www.webmd.com/drugs/2/drug-2247/coricidin-hbp-cough-and-cold-oral/details/list-sideeffects "Coricidin HBP Cough and Cold"], WebMD. Retrieved 7 January 2017.

Recreational use

{{See also|Recreational use of dextromethorphan}}

Coricidin, in its cough & cold formulation, is sometimes used in high doses as a recreational drug because it contains the dissociative dextromethorphan. In this context, Coricidin is referred to as Cs, Red Devils (Red Ds), Triple Cs, Skittles, trips, or china red.{{cite journal | vauthors = Silva AR, Dinis-Oliveira RJ | title = Pharmacokinetics and pharmacodynamics of dextromethorphan: clinical and forensic aspects | journal = Drug Metabolism Reviews | volume = 52 | issue = 2 | pages = 258–282 | date = May 2020 | pmid = 32393072 | doi = 10.1080/03602532.2020.1758712 }}

Notes

{{Reflist}}