Corynebacterium freneyi
{{Short description|Species of Gram-positive bacterium}}
{{Speciesbox
| taxon = Corynebacterium freneyi
| authority = Renaud et al. 2001
}}
Corynebacterium freneyi is a species of Gram-positive, non-motile, non-spore-forming, rod-shaped bacterium in the genus Corynebacterium. It was first described in 2001 by Renaud et al. based on α-glucosidase-positive strains related to Corynebacterium xerosis.{{cite journal |last1=Renaud |first1=F.N.R. |last2=Aubel |first2=D. |last3=Riegel |first3=P. |last4=Meugnier |first4=H. |last5=Bollet |first5=C. |title=Corynebacterium freneyi sp. nov., alpha-glucosidase-positive strains related to Corynebacterium xerosis |journal=International Journal of Systematic and Evolutionary Microbiology |volume=51 |issue=5 |pages=1723–1728 |date=2001 |doi=10.1099/00207713-51-5-1723}}
Taxonomy
C. freneyi was initially identified from clinical isolates that exhibited α-glucosidase activity and biochemical profiles similar to C. xerosis. However, molecular analyses, including 16S rRNA gene sequencing and restriction fragment length polymorphism (RFLP) of the 16S-23S rRNA intergenic spacer region, demonstrated that C. freneyi is a distinct species.{{cite journal |last1=Funke |first1=G. |last2=Frodl |first2=R. |title=Comprehensive study of Corynebacterium freneyi strains and extended and emended description of Corynebacterium freneyi Renaud, Aubel, Riegel, Meugnier, and Bollet 2001 |journal=Journal of Clinical Microbiology |volume=46 |issue=2 |pages=638–643 |date=2008 |doi=10.1128/JCM.01491-07}}
Clinical significance
Although initially considered a rare isolate, C. freneyi has been implicated in various clinical specimens, including those from the female genital tract. Its pathogenic potential remains under investigation, but it has been associated with bacteremia and prosthetic valve endocarditis in isolated cases.{{cite journal |last1=Author |first1=Name |title=Corynebacterium freneyi as a cause of early prosthetic valve endocarditis |journal=BMJ Case Reports |volume=14 |issue=11 |pages=e245152 |date=2021 |doi=10.1136/bcr-2021-245152}}
Type strain
The type strain of C. freneyi is CCUG 45704 (= CIP 106767 = DSM 44506 = JCM 12104).{{cite web |title=Species: Corynebacterium freneyi |url=https://lpsn.dsmz.de/species/corynebacterium-freneyi |website=List of Prokaryotic names with Standing in Nomenclature (LPSN) |access-date=2025-06-10}}
References
{{Reflist}}
External links
- [https://lpsn.dsmz.de/species/corynebacterium-freneyi LPSN – Corynebacterium freneyi]
- [https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=134034 NCBI Taxonomy Browser – Corynebacterium freneyi]
- [https://www.bacdive.dsmz.de/strain/135461 BacDive – Corynebacterium freneyi strain CIP 52.16]