Cosavirus

{{Short description|Genus of viruses}}

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Cosavirus is a genus of viruses in the order Picornavirales, in the family Picornaviridae. Human serve as natural hosts. There are 5 species in this genus.{{cite web|title=Viral Zone|url=http://viralzone.expasy.org/all_by_species/4797.html|publisher=ExPASy|accessdate=13 August 2015}}{{cite web|title=Virus Taxonomy: 2024 Release|url=https://ictv.global/taxonomy|publisher=International Committee on Taxonomy of Viruses|access-date=12 April 2025}}

It is unclear whether cosaviruses are connected to gastroenteritis in humans.{{Cite web|url=https://journals.lww.com/pidj/pages/articleviewer.aspx?year=2016&issue=01000&article=00024&type=Fulltext|title=Newly Identified Viruses in Human Gastroenteritis|last=|first=|date=January 2016|website=The Pediatric Infectious Disease Journal|url-status=live|archive-url=https://web.archive.org/web/20160617055403/http://journals.lww.com/pidj/pages/articleviewer.aspx?year=2016&issue=01000&article=00024&type=Fulltext |archive-date=17 June 2016 |access-date=2020-03-08}}

Taxonomy

The genus contains the following species, listed by scientific name:{{cite web |title=Species List: Picornaviridae |url=https://ictv.global/report/chapter/picornaviridae/taxonomy/picornaviridae |publisher=International Committee on Taxonomy of Viruses |access-date=12 April 2025}}

  • Cosavirus asiani, Cosavirus A
  • Cosavirus bepakis, Cosavirus B
  • Cosavirus depakis, Cosavirus D
  • Cosavirus eaustrali, Cosavirus E
  • Cosavirus fepakis, Cosavirus F

Structure

Viruses in Cosavirus are non-enveloped, with icosahedral, spherical, and round geometries, and T=pseudo3 symmetry. The diameter is around 30 nm. Genomes are linear and non-segmented, around 7-8kb in length.

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GenusStructure || SymmetryCapsidGenomic arrangementGenomic segmentation
CosavirusIcosahedralPseudo T=3Non-envelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the virus to host receptors, which mediates endocytosis. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. Translation takes place by ribosomal skipping. The virus exits the host cell by lysis, and viroporins. Human serve as the natural host. Transmission routes are fecal-oral.

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GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
CosavirusHumanNoneCell receptor endocytosisUnknownCytoplasmCytoplasmUnknown

References

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