Cranioschisis
{{short description|Neural tube defect in which the brain is exposed}}
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Cranioschisis ({{langx|el|κρανιον kranion}}, "skull", and σχίσις schisis, "split") is a skull-related neural tube defect. The skull does not close all the way in this deformity (especially at the occipital region). As a result, the amniotic fluid enters the brain, leading to eventual brain degeneration and anencephaly.{{cite book | last=Singh | first=D.R. | title=Essentials of Anatomy for Dentistry Students | publisher=Wolters Kluwer India Pvt. Limited | year=2017 | isbn=978-93-5129-620-1 |url=https://books.google.com/books?id=evbsDwAAQBAJ&pg=PA359 | access-date=January 2, 2024 | page=359}} Craniorachischisis is on the extreme end of the dysraphism spectrum, wherein the entire length of the neural tube fails to close.{{cite book |title=Larsen's Human Embryology |date=2015 |publisher=Churchill Livingstone |pages=81–107 |edition=5}}
See also
References
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Further reading
- {{cite journal | last=Marin-Padilla | first=Miguel | title=Study of the Skull in Human Cranioschisis | journal=Cells Tissues Organs | publisher=S. Karger AG | volume=62 | issue=1 | year=1965 | issn=1422-6405 | doi=10.1159/000142740 | pages=1–20 | pmid=5864445 | ref=none}}
- {{cite journal | last=Padmanabhan | first=R. | title=Light microscopic studies on the pathogenesis of exencephaly and cranioschisis induced in the rat after neural tube closure | journal=Teratology | volume=37 | issue=1 | date=1988 | issn=0040-3709 | doi=10.1002/tera.1420370106 | pages=29–36 | pmid=3347905 | ref=none}}
External links
- [https://www.informatics.jax.org/vocab/mp%20ontology/MP:0000919 Mouse Genome Informatics]
- [https://www.yourdictionary.com/cranioschisis YourDictionary]
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| ICD10 = {{ICD10|Q07.9}}
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| MeshID = D009421
| DiseasesDB = 34559
| SNOMED CT = 48777005
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{{Congenital malformations and deformations of musculoskeletal system}}
Category:Congenital disorders of nervous system
Category:Congenital disorders of musculoskeletal system
{{Congenital-malformation-stub|}}