DCP1A

DCP1A has been shown to interact with DCP2{{cite journal | vauthors = Lykke-Andersen J | title = Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay | journal = Molecular and Cellular Biology | volume = 22 | issue = 23 | pages = 8114–8121 | date = December 2002 | pmid = 12417715 | pmc = 134073 | doi = 10.1128/MCB.22.23.8114-8121.2002 }} and UPF1. It has also been shown to colocalize with GW182, and other markers of P-body.{{cite journal | vauthors = Eystathioy T, Jakymiw A, Chan EK, Séraphin B, Cougot N, Fritzler MJ | title = The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies | journal = RNA | volume = 9 | issue = 10 | pages = 1171–1173 | date = October 2003 | pmid = 13130130 | pmc = 1370480 | doi = 10.1261/rna.5810203 }} Human DCP1A is heterotrimeric,{{cite journal | vauthors = Tritschler F, Braun JE, Motz C, Igreja C, Haas G, Truffault V, Izaurralde E, Weichenrieder O | display-authors = 6 | title = DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 106 | issue = 51 | pages = 21591–21596 | date = December 2009 | pmid = 19966221 | pmc = 2789166 | doi = 10.1073/pnas.0909871106 | doi-access = free | bibcode = 2009PNAS..10621591T }} and makes contacts with the scaffold EDC3/4.{{cite journal | vauthors = Tritschler F, Eulalio A, Truffault V, Hartmann MD, Helms S, Schmidt S, Coles M, Izaurralde E, Weichenrieder O | display-authors = 6 | title = A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting | journal = Molecular and Cellular Biology | volume = 27 | issue = 24 | pages = 8600–8611 | date = December 2007 | pmid = 17923697 | pmc = 2169425 | doi = 10.1128/MCB.01506-07 }} The Arabidopsis thaliana homolog interacts with the plant specific type XI myosin motor protein.{{cite journal | vauthors = Steffens A, Jaegle B, Tresch A, Hülskamp M, Jakoby M | title = Processing-body movement in Arabidopsis depends on an interaction between myosins and DECAPPING PROTEIN1 | journal = Plant Physiology | volume = 164 | issue = 4 | pages = 1879–1892 | date = April 2014 | pmid = 24525673 | pmc = 3982750 | doi = 10.1104/pp.113.233031 | doi-access = free }}

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• {{cite journal | vauthors = Fenger-Grøn M, Fillman C, Norrild B, Lykke-Andersen J | title = Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping | journal = Molecular Cell | volume = 20 | issue = 6 | pages = 905–915 | date = December 2005 | pmid = 16364915 | doi = 10.1016/j.molcel.2005.10.031 | doi-access = free }}
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{{Post transcriptional modification}}

{{gene-3-stub}}