DDS

• Digimon Data Squad, season 5 of the anime Digimon.
• Shin Megami Tensei: Digital Devil Saga, a 2004 video game spun off from the Shin Megami Tensei series
• Dmitri Dmitriyevich Shostakovich, Russian composer
• Death's Dynamic Shroud, American electronic and vaporwave trio

• Disability Determination Service, a state agency in the United States that determines eligibility for federal disability benefits
• Department of Driver Services, also known as Department of Motor Vehicles
• Due Diligence System

• Davao Death Squad, a vigilante group in Davao City, Philippines
• Davidson Day School, a pre-K–12 school in Davidson, North Carolina, United States
• De Danske Skytteforeninger, a Danish sports organization
• Diehard Duterte Supporters, supporters of Rodrigo Duterte, 16th president of the Philippines
• Donovan Data Systems, a software and computer services company
• Dutchess Day School, private pre-K through 8th grade school in Millbrook, New York, United States

• Dimethyldichlorosilane, an organosilicon compound
• Dammarenediol II synthase, an enzyme

• Data Design System, a CAD software system
• Direct Digital Synthesis / Direct digital synthesizer, a method for generation of periodic digital signals and used for creating arbitrary waveforms from a reference clock
• Data Definition Specification, in software data management
• Data Description Specifications, in AS/400 programming
• Data Distribution Service, an Object Management Group standard for publish/subscribe middleware for distributed systems
• Data dictionary system of ICL's VME operating system; see ICL VME#QuickBuild
• Dataphone Digital Service or Digital Data System, types of leased line
• Digital Data Storage, a storage tape format related to Digital Audio Tape (DAT)
• Dimensional Data Storage
• DirectDraw Surface, .dds texture files
• Dynamic digital signage

• Dapsone, also known as diaminodiphenyl sulfone (DDS), an antibiotic commonly used for the treatment of leprosy
• Doctor of Dental Surgery, an academic degree
• Dopamine dysregulation syndrome, a condition connected with treatment for Parkinson's disease
• Drug delivery systems, how drugs are delivered to relevant areas or tissues

• Dark dune spot, a feature of the Martian landscape
• Deflation Detection System, on motor vehicle tires
• Dry deck shelter, a module that allows divers easy exit and entrance while a submarine is submerged

• Dewey Decimal Classification, often called the Dewey Decimal System
• Direct Delivery Scheme, of the Society of Independent Brewers

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