DHRS1

The DHRS1 gene is located on the chromosome 14q21.3 region and contains 9 exons. It encodes a 314-amino-acid, 33-kDa protein that is thought to be located to the endoplasmic reticulum and the mitochondrial inner membrane inside the cell.

The DHRS1 protein is thought to have oxidoreductase activity based on sequence similarity and conserved catalytic sites with other short-chain oxidoreductase enzymes. The enzyme is found to be expressed in the fetal brain.{{cite journal |vauthors=Wu Q, Xu M, Cheng C, Zhou Z, Huang Y, Zhao W, Zeng L, Xu J, Fu X, Ying K, Xie Y, Mao Y |title=Molecular cloning and characterization of a novel Dehydrogenase/reductase (SDR family) member 1 genea from human fetal brain |journal=Mol. Biol. Rep. |volume=28 |issue=4 |pages=193–8 |year=2001 |pmid=12153138 |doi= 10.1023/A:1015722001960 |s2cid=29552121 }}

The DHRS1 protein is thought to interact with the protein phospholipid scrambase 1 (PLSCR1).{{Cite web|url=http://www.ebi.ac.uk/intact/pages/interactions/interactions.xhtml?query=Q96LJ7*|title = IntAct Portal}}

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Category:Genes

Category:Human proteins

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