DIS3L

{{Short description|Protein-coding gene in the species Homo sapiens}}

DIS3-like exonuclease 1 (Dis3L1 or Dis3L) is an enzyme that in humans is encoded by the DIS3L gene. Its protein product is an RNase enzyme homologous to the yeast protein Rrp44, and can be part of the exosome complex in the cytoplasm of eukaryotic cells.

References

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{{cite journal |vauthors=Staals RH, Bronkhorst AW, Schilders G, Slomovic S, Schuster G, Heck AJ, Raijmakers R, Pruijn GJ | title = Dis3-like 1: a novel exoribonuclease associated with the human exosome | journal = EMBO J. | volume = 29 | issue = 14 | pages = 2358–67 |date=July 2010 | pmid = 20531389 | doi = 10.1038/emboj.2010.122 | pmc=2910272}}

{{cite journal |vauthors=Tomecki R, Kristiansen MS, Lykke-Andersen S, Chlebowski A, Larsen KM, Szczesny RJ, Drazkowska K, Pastula A, Andersen JS, Stepien PP, Dziembowski A, Jensen TH | title = The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L | journal = EMBO J. | volume = 29 | issue = 14 | pages = 2342–57 |date=July 2010 | pmid = 20531386 | doi = 10.1038/emboj.2010.121 | pmc=2910271}}

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Category:EC 3.1.13