DIXDC1
{{Short description|Protein-coding gene in humans}}
{{Infobox_gene}}
Dixin is a protein that in humans is encoded by the DIXDC1 gene.{{cite journal | vauthors = Katoh M, Katoh M | title = KIAA1735 gene on human chromosome 11q23.1 encodes a novel protein with myosine-tail homologous domain and C-terminal DIX domain | journal = International Journal of Oncology | volume = 23 | issue = 1 | pages = 145–50 | date = July 2003 | pmid = 12792787 | doi = 10.3892/ijo.23.1.145 }}{{cite web | title = Entrez Gene: DIXDC1 DIX domain containing 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=85458}} When active it stops cancer metastasis due to extreme stickiness, both in vitro and in vivo.{{Cite web|url=http://medicalxpress.com/news/2014-07-gene-deadly-cancer.html#nRlv|title=New gene discovered that stops the spread of deadly cancer}}
References
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Further reading
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- {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Analytical Biochemistry | volume = 236 | issue = 1 | pages = 107–13 | date = April 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}
- {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-scale concatenation cDNA sequencing | journal = Genome Research | volume = 7 | issue = 4 | pages = 353–8 | date = April 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
- {{cite journal | vauthors = Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Research | volume = 7 | issue = 6 | pages = 347–55 | date = December 2000 | pmid = 11214970 | doi = 10.1093/dnares/7.6.347 | doi-access = free }}
- {{cite journal | vauthors = Ohira M, Morohashi A, Inuzuka H, Shishikura T, Kawamoto T, Kageyama H, Nakamura Y, Isogai E, Takayasu H, Sakiyama S, Suzuki Y, Sugano S, Goto T, Sato S, Nakagawara A | title = Expression profiling and characterization of 4200 genes cloned from primary neuroblastomas: identification of 305 genes differentially expressed between favorable and unfavorable subsets | journal = Oncogene | volume = 22 | issue = 35 | pages = 5525–36 | date = August 2003 | pmid = 12934113 | doi = 10.1038/sj.onc.1206853 | doi-access = free }}
- {{cite journal | vauthors = Wong CK, Luo W, Deng Y, Zou H, Ye Z, Lin SC | title = The DIX domain protein coiled-coil-DIX1 inhibits c-Jun N-terminal kinase activation by Axin and dishevelled through distinct mechanisms | journal = The Journal of Biological Chemistry | volume = 279 | issue = 38 | pages = 39366–73 | date = September 2004 | pmid = 15262978 | doi = 10.1074/jbc.M404598200 | doi-access = free }}
- {{cite journal | vauthors = Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S | title = Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes | journal = Genome Research | volume = 16 | issue = 1 | pages = 55–65 | date = January 2006 | pmid = 16344560 | pmc = 1356129 | doi = 10.1101/gr.4039406 }}
- {{cite journal | vauthors = Wang X, Zheng L, Zeng Z, Zhou G, Chien J, Qian C, Vasmatzis G, Shridhar V, Chen L, Liu W | title = DIXDC1 isoform, l-DIXDC1, is a novel filamentous actin-binding protein | journal = Biochemical and Biophysical Research Communications | volume = 347 | issue = 1 | pages = 22–30 | date = August 2006 | pmid = 16814745 | doi = 10.1016/j.bbrc.2006.06.050 }}
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