DME

• DME (psychedelic), 3,4-dimethoxy-beta-hydroxyphenethylamine, a psychedelic drug
• Dimethoxyethane, a solvent
• Dimethylethanolamine, a precursor molecule for C-choline
• Dimethyl ether, a fuel and an aerosol spray propellant

• Diabetic macular edema
• Durable medical equipment

• Dashtop mobile equipment
• Diastatic malt extract, used in home-brewing
• Distance measuring equipment, used in aviation
• Dropping mercury electrode, used in polarography
• ICL Direct Machine Environment, an operating system

• Delhi–Mumbai Expressway, in India
• Dakota, Minnesota and Eastern Railroad
• Disney's Magical Express, at Walt Disney World
• Moscow Domodedovo Airport, serving Moscow, Russia

• Design Management Europe Award
• DME Academy, in Daytona Beach, Florida
• Dubai Mercantile Exchange
• Ɗugwor language
• United States District Court for the District of Maine
• Durium Marche Estere, a sub-label of Durium Records

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