DPT-Hib vaccine

{{Short description|Combination vaccine}}

{{Infobox drug

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| drug_name =

| type = combo

| component1 = Diphtheria vaccine

| class1 = Vaccine

| component2 = Tetanus vaccine

| class2 = Vaccine

| component3 = Pertussis vaccine

| class3 = Vaccine

| component4 = Hib vaccine

| class4 = Vaccine

| pronounce =

| tradename = Tetramune

| Drugs.com = {{drugs.com|cons|DPT-Hib}}

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| pregnancy_AU =

| pregnancy_US = C

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| routes_of_administration = Intramuscular injection

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| ATCvet =

| ATC_prefix = J07

| ATC_suffix = AG52

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DPT-Hib vaccine is a combination vaccine whose generic name is diphtheria and tetanus toxoids and whole-cell pertussis vaccine adsorbed with Hib conjugate vaccine, sometimes abbreviated to DPT-Hib.{{cite web|url=https://www.drugs.com/cons/DPT-Hib.html|title=Diphtheria and Tetanus Toxoids and Pertussis Vaccine Adsorbed and Haemophilus B Conjugate Vaccine (Systemic)|publisher=Drugs.com|access-date=15 July 2018|archive-date=15 July 2018|archive-url=https://web.archive.org/web/20180715210957/https://www.drugs.com/cons/DPT-Hib.html|url-status=dead}} It protects against the infectious diseases diphtheria, tetanus, pertussis, and Haemophilus influenzae type B.

A branded formulation was marketed in the US as Tetramune by Lederle Praxis Biologicals (subsequently acquired by Wyeth).{{cite journal | title = FDA approval of use of a new Haemophilus b conjugate vaccine and a combined diphtheria-tetanus-pertussis and Haemophilus b conjugate vaccine for infants and children | journal = MMWR. Morbidity and Mortality Weekly Report | volume = 42 | issue = 15 | pages = 296–8 | date = April 1993 | pmid = 8479415 | url = https://www.cdc.gov/mmwr/preview/mmwrhtml/00020301.htm | access-date = 15 July 2018 | publisher = Centers for Disease Control and Prevention | author1 = Centers for Disease Control Prevention (CDC) }} Tetramune has since been discontinued.{{cite web|url=https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/discontinued_vaccines.pdf|title=Selected Discontinued U.S. Vaccines|publisher=Centers for Disease Control and Prevention|access-date=15 July 2018}}{{cite journal | vauthors = Zarei AE, Almehdar HA, Redwan EM | title = Hib Vaccines: Past, Present, and Future Perspectives | journal = Journal of Immunology Research | volume = 2016 | issue = | pages = 7203587 | date = 2016 | pmid = 26904695 | pmc = 4745871 | doi = 10.1155/2016/7203587 | quote = Table 1 | doi-access = free }}