DYNLL2

{{Short description|Protein-coding gene in the species Homo sapiens}}

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{{Infobox_gene}}

Dynein light chain 2, cytoplasmic is a protein that in humans is encoded by the DYNLL2 gene.{{cite journal | vauthors = Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB | title = Cytoplasmic dynein nomenclature | journal = The Journal of Cell Biology | volume = 171 | issue = 3 | pages = 411–413 | date = November 2005 | pmid = 16260502 | pmc = 2171247 | doi = 10.1083/jcb.200508078 }}{{cite web | title = Entrez Gene: DYNLL2 dynein, light chain, LC8-type 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=140735}}

Interactions

DYNLL2 has been shown to interact with DLG4,{{cite journal | vauthors = Naisbitt S, Valtschanoff J, Allison DW, Sala C, Kim E, Craig AM, Weinberg RJ, Sheng M | title = Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein | journal = The Journal of Neuroscience | volume = 20 | issue = 12 | pages = 4524–4534 | date = June 2000 | pmid = 10844022 | pmc = 6772433 | doi = 10.1523/JNEUROSCI.20-12-04524.2000 | doi-access = free }} C12orf40,{{cite journal | vauthors = Rolland T, Taşan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, Begg BE, Braun P, Brehme M, Broly MP, Carvunis AR, Convery-Zupan D, Corominas R, Coulombe-Huntington J, Dann E, Dreze M, Dricot A, Fan C, Franzosa E, Gebreab F, Gutierrez BJ, Hardy MF, Jin M, Kang S, Kiros R, Lin GN, Luck K, MacWilliams A, Menche J, Murray RR, Palagi A, Poulin MM, Rambout X, Rasla J, Reichert P, Romero V, Ruyssinck E, Sahalie JM, Scholz A, Shah AA, Sharma A, Shen Y, Spirohn K, Tam S, Tejeda AO, Wanamaker SA, Twizere JC, Vega K, Walsh J, Cusick ME, Xia Y, Barabási AL, Iakoucheva LM, Aloy P, De Las Rivas J, Tavernier J, Calderwood MA, Hill DE, Hao T, Roth FP, Vidal M | title = A proteome-scale map of the human interactome network | journal = Cell | volume = 159 | issue = 5 | pages = 1212–1226 | date = November 2014 | pmid = 25416956 | pmc = 4266588 | doi = 10.1016/j.cell.2014.10.050 }} DLGAP1, MYO5A{{cite journal | vauthors = Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, Huang DC, Strasser A | title = Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis | journal = Science | volume = 293 | issue = 5536 | pages = 1829–1832 | date = September 2001 | pmid = 11546872 | doi = 10.1126/science.1062257 | s2cid = 5638023 | bibcode = 2001Sci...293.1829P }} and BMF.{{cite journal | vauthors = Day CL, Puthalakath H, Skea G, Strasser A, Barsukov I, Lian LY, Huang DC, Hinds MG | title = Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands | journal = The Biochemical Journal | volume = 377 | issue = Pt 3 | pages = 597–605 | date = February 2004 | pmid = 14561217 | pmc = 1223895 | doi = 10.1042/BJ20031251 }}

References

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Further reading

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  • {{cite journal | vauthors = Naisbitt S, Valtschanoff J, Allison DW, Sala C, Kim E, Craig AM, Weinberg RJ, Sheng M | title = Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein | journal = The Journal of Neuroscience | volume = 20 | issue = 12 | pages = 4524–4534 | date = June 2000 | pmid = 10844022 | pmc = 6772433 | doi = 10.1523/JNEUROSCI.20-12-04524.2000 | doi-access = free }}
  • {{cite journal | vauthors = Haraguchi K, Satoh K, Yanai H, Hamada F, Kawabuchi M, Akiyama T | title = The hDLG-associated protein DAP interacts with dynein light chain and neuronal nitric oxide synthase | journal = Genes to Cells | volume = 5 | issue = 11 | pages = 905–911 | date = November 2000 | pmid = 11122378 | doi = 10.1046/j.1365-2443.2000.00374.x | s2cid = 37107139 | doi-access = free }}
  • {{cite journal | vauthors = Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, Huang DC, Strasser A | title = Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis | journal = Science | volume = 293 | issue = 5536 | pages = 1829–1832 | date = September 2001 | pmid = 11546872 | doi = 10.1126/science.1062257 | s2cid = 5638023 | bibcode = 2001Sci...293.1829P }}
  • {{cite journal | vauthors = Fuhrmann JC, Kins S, Rostaing P, El Far O, Kirsch J, Sheng M, Triller A, Betz H, Kneussel M | title = Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes | journal = The Journal of Neuroscience | volume = 22 | issue = 13 | pages = 5393–5402 | date = July 2002 | pmid = 12097491 | pmc = 6758200 | doi = 10.1523/JNEUROSCI.22-13-05393.2002 | doi-access = free }}
  • {{cite journal | vauthors = Day CL, Puthalakath H, Skea G, Strasser A, Barsukov I, Lian LY, Huang DC, Hinds MG | title = Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands | journal = The Biochemical Journal | volume = 377 | issue = Pt 3 | pages = 597–605 | date = February 2004 | pmid = 14561217 | pmc = 1223895 | doi = 10.1042/BJ20031251 }}
  • {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–1178 | date = October 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | s2cid = 4427026 | bibcode = 2005Natur.437.1173R }}

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Further reading

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  • {{cite journal | vauthors = Donner J, Pirkola S, Silander K, Kananen L, Terwilliger JD, Lönnqvist J, Peltonen L, Hovatta I | title = An association analysis of murine anxiety genes in humans implicates novel candidate genes for anxiety disorders | journal = Biological Psychiatry | volume = 64 | issue = 8 | pages = 672–680 | date = October 2008 | pmid = 18639233 | pmc = 2682432 | doi = 10.1016/j.biopsych.2008.06.002 }}

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