Daniela Rhodes

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Nanyang Technological University
Laboratory of Molecular Biology{{cite web|archive-url=https://archive.today/20151208035604/http://www2.mrc-lmb.cam.ac.uk/group-leaders/emeritus/daniela-rhodes/|archive-date=8 December 2015|url=http://www2.mrc-lmb.cam.ac.uk/group-leaders/emeritus/daniela-rhodes/|publisher=Laboratory of Molecular Biology|title=Emeritus Scientist: Daniela Rhodes}}}}

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| alma_mater = University of Cambridge

| thesis_title = The helical periodicity of DNA in solution and in chromatin

| thesis_url = http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.257701

| thesis_year = 1982

| doctoral_advisor = Aaron Klug

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| awards = FRS (2007);{{cite web|archive-url=https://web.archive.org/web/20151117110822/https://royalsociety.org/people/daniela-rhodes-12168/|archive-date=17 November 2015|url=https://royalsociety.org/people/daniela-rhodes-12168/|publisher=Royal Society|location=London|title=Professor Daniela Rhodes FRS}}

The WLA Prize in Life Science or Medicine (2023)

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Daniela Bargellini Rhodes FRS (born 1946) is an Italian structural and molecular biologist. She was a senior scientist at the Laboratory of Molecular Biology in Cambridge, England,{{cite web |url=http://www.set-routes.org/conference/speakers/rhodes.html |title=International Conference – Speakers – Daniela Rhodes |publisher=SET-Routes |date=1 April 2008 |access-date=2 January 2014 |archive-date=3 March 2016 |archive-url=https://web.archive.org/web/20160303174831/http://www.set-routes.org/conference/speakers/rhodes.html |url-status=dead }} where she worked, and later studied for her PhD{{cite thesis|degree=PhD|publisher=University of Cambridge|title=The helical periodicity of DNA in solution and in chromatin.|first= Daniela|last=Rhodes|year=1982|url=http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.257701|oclc=556524059}} under the supervision of Nobel laureate Aaron Klug. Continuing her work under the tutelage of Aaron Klug at Cambridge, she was appointed group leader in 1983, obtained tenure in 1987 and was promoted to senior scientist in 1994 (equivalent to full professor). Subsequently, she served as director of studies between 2003 and 2006. She has also been visiting professor at both "La Sapienza" in Rome, Italy and the Rockefeller University in NY, USA.[https://books.google.com/books?id=hjO5Uoc7GaYC&dq=Daniela+Rhodes&pg=PA215 "Analysis of sequence-specific DNA-binging proteins"], Protein function: a practical approach, Editor Thomas E. Creighton, Oxford University Press, 1997, {{ISBN|978-0-19-963615-0}}[https://books.google.com/books?id=tVnxXiIB4CAC&dq=Daniela+Rhodes&pg=PA191 "The Role of Histone H1 in Chromatin Condensation and Transcriptional Repression"], Structural biology and functional genomics, Editors E. Morton Bradbury, Sándor Pongor, Springer, 1999, {{ISBN|978-0-7923-5781-0}}[https://books.google.com/books?id=beWBOadOf9AC&dq=Daniela+Rhodes&pg=PA139 "Telomeric DNA Recognition"], RNA biochemistry and biotechnology, Volume 1998, Editors Jan Barciszewski, Brian Frederic Carl Clark, Springer, 1999, {{ISBN|978-0-7923-5861-9}}"Structure of the 30nm Chromatin Fibre and the Regulation of Its Compaction" {{cite web |url=http://www.med.unc.edu/biochem/events/past-events/seminars/daniela-rhodes-phd |title=Daniela Rhodes, PhD – Biochemistry and Biophysics |publisher=University of North Carolina School of Medicine |date=22 April 2008 |access-date=2 January 2014 |archive-url=https://web.archive.org/web/20120926105048/http://www.med.unc.edu/biochem/events/past-events/seminars/daniela-rhodes-phd/ |archive-date=26 September 2012 |url-status=dead }}[http://en.scientificcommons.org/daniela_rhodes Daniela Rhodes's profile at Scientific Commons]

Career and research

Daniela Rhodes has made many fundamental contributions to understanding the structure and function of nucleic acids and their biologically important interactions with many different proteins. Her work combines biochemical analyses with direct structural determination. She determined the structures of a number of important protein-DNA complexes involved in transcription, such as zinc-fingers and nuclear hormone receptors. She has provided some of the first structural information on telomeric proteins, such as yeast Rap1p and human TRF1 and TRF2 and their complexes with DNA. Throughout her career she has made many contributions to the understanding of chromatin structure and function. She was involved in determining the structure of the nucleosome core particle, has worked on transcriptionally active chromatin and more recently on the higher order 30nm structure of chromatin. Her research continues to focus on understanding how the structure of chromatin is involved in transcriptional regulation and how telomeres are involved in preserving chromosome integrity.[http://www2.mrc-lmb.cam.ac.uk/SS/Rhodes_D/ LMB Web-page] {{webarchive|url=https://web.archive.org/web/20090330131831/http://www2.mrc-lmb.cam.ac.uk/ss/Rhodes_D/ |date=30 March 2009 }}

She joined the School of Biological Sciences at Nanyang Technological University (NTU), in Singapore, as professor in September 2011{{cite web|url=http://research.ntu.edu.sg/expertise/academicprofile/pages/StaffProfile.aspx?ST_EMAILID=DRHODES |title=Academic Profile: Professor Daniela Rhodes |publisher=Nanyang Technological University |date=4 August 2009 |access-date=2 January 2014}} and was additionally appointed professor at the Lee Kong Chian School of Medicine in September 2012.{{cite web|url=http://www.lkcmedicine.ntu.edu.sg/Research/researchfaculty/Pages/Prof-Daniela-Rhodes.aspx |archive-url=https://archive.today/20140403133439/http://www.lkcmedicine.ntu.edu.sg/Research/researchfaculty/Pages/Prof-Daniela-Rhodes.aspx |url-status=dead |archive-date=2014-04-03 |title=Academic Profile: Professor Daniela Rhodes |publisher=LKC School of Medicine |date=4 August 2009 |access-date=3 April 2014 }} In April 2014 she was appointed Director of the newly formed Nanyang Institute of Structural Biology.

Daniela left NTU in 2020 and is an Emeritus Scientist at the Laboratory of Molecular Biology.

Awards and honours

Laureate of the 2023 [https://www.thewlaprize.org/ World Laureates Association Prize in Life Science or Medicine] (With Timothy J. Richmond and Karolin Luger){{cite web |title=Laureates of the 2023 WLA Prize Announced |url=https://www.thewlaprize.org/PressRoom/News/2023/09/14/179.html |website=The WLA Prize}}
Elected a Fellow of the Royal Society (FRS) in 2007
Elected member of EMBO as of 1996.
Elected member of Academia Europaea as of 2011.
She is a Fellow of Clare Hall, Cambridge.
Asteroid 80008 Danielarhodes, discovered by Italian astronomers Luciano Tesi and Andrea Boattini in 1999, was named in her honor. The official {{MoMP|80008|naming citation}} was published by the Minor Planet Center on 10 December 2011 ({{small|M.P.C. 77507}}).